&#945;O-Conotoxin GeXIVA Inhibits the Growth of Breast Cancer Cells via Interaction with &#945;9 Nicotine Acetylcholine Receptors.

Sun, Zhihua; Bao, Jiaolin; Zhangsun, Manqi; Dong, Shuai; Zhangsun, Dongting; Luo, Sulan

αO-Conotoxin GeXIVA Inhibits the Growth of Breast Cancer Cells via Interaction with α9 Nicotine Acetylcholine Receptors.

Sun, Zhihua; Bao, Jiaolin; Zhangsun, Manqi; Dong, Shuai; Zhangsun, Dongting; Luo, Sulan.

Afiliação

Sun Z; Key Laboratory of Tropical Biological Resources of Ministry of Education, Key Laboratory for Marine Drugs of Haikou, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Bao J; Key Laboratory of Tropical Biological Resources of Ministry of Education, Key Laboratory for Marine Drugs of Haikou, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Zhangsun M; Key Laboratory of Tropical Biological Resources of Ministry of Education, Key Laboratory for Marine Drugs of Haikou, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Dong S; Key Laboratory of Tropical Biological Resources of Ministry of Education, Key Laboratory for Marine Drugs of Haikou, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Zhangsun D; Medical School, Guangxi University, Nanning 530004, China.
Luo S; Key Laboratory of Tropical Biological Resources of Ministry of Education, Key Laboratory for Marine Drugs of Haikou, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China.

Mar Drugs ; 18(4)2020 Apr 07.

Article em En | MEDLINE | ID: mdl-32272701

Assuntos

Proliferação de Células/efeitos dos fármacos; Conotoxinas/farmacologia; Antagonistas Nicotínicos/farmacologia; Receptores Nicotínicos/efeitos dos fármacos; Neoplasias da Mama/tratamento farmacológico; Ciclo Celular/efeitos dos fármacos; Linhagem Celular Tumoral; Movimento Celular/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Feminino; Humanos; Receptores Nicotínicos/deficiência; Receptores Nicotínicos/metabolismo

Palavras-chave

anti-proliferation; apoptosis; breast cancer cells; targeted therapy; α9-nicotinic acetylcholine receptors (nAChRs); αO-conotoxin GeXIVA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Nicotínicos / Antagonistas Nicotínicos / Conotoxinas / Proliferação de Células Limite: Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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