Sirt3 modulates fatty acid oxidation and attenuates cisplatin-induced AKI in mice.

Li, Ming; Li, Can-Ming; Ye, Zeng-Chun; Huang, Jiayan; Li, Yin; Lai, Weiyan; Peng, Hui; Lou, Tan-Qi

Li, Ming; Li, Can-Ming; Ye, Zeng-Chun; Huang, Jiayan; Li, Yin; Lai, Weiyan; Peng, Hui; Lou, Tan-Qi.

Afiliação

Li M; Division of Nephrology, Department of Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Li CM; Division of Nephrology, Department of Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Ye ZC; Division of Nephrology, Department of Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Huang J; Division of Nephrology, Department of Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Li Y; Division of Nephrology, Department of Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Lai W; Division of Nephrology, Department of Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Peng H; Division of Nephrology, Department of Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Lou TQ; Division of Nephrology, Department of Medicine, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

J Cell Mol Med ; 24(9): 5109-5121, 2020 05.

Article em En | MEDLINE | ID: mdl-32281286

Assuntos

Injúria Renal Aguda/induzido quimicamente; Cisplatino/farmacologia; Ácidos Graxos/metabolismo; Sirtuína 3/metabolismo; Acetilação; Injúria Renal Aguda/metabolismo; Animais; Antineoplásicos/farmacologia; Apoptose; Compostos de Bifenilo; Ácidos Graxos não Esterificados/metabolismo; Testes de Função Renal; Lignanas; Metabolismo dos Lipídeos; Peroxidação de Lipídeos; Lipídeos/química; Masculino; Metabolômica; Camundongos; Camundongos Knockout; Mitocôndrias/metabolismo; Fosforilação; Prognóstico; Espécies Reativas de Oxigênio; Sirtuína 3/genética

Palavras-chave

Sirtuin3; acute kidney injury; cisplatin; fatty acid oxidation; mitochondrion

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisplatino / Ácidos Graxos / Sirtuína 3 / Injúria Renal Aguda Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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