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On the Alert for Cytokine Storm: Immunopathology in COVID-19.
Henderson, Lauren A; Canna, Scott W; Schulert, Grant S; Volpi, Stefano; Lee, Pui Y; Kernan, Kate F; Caricchio, Roberto; Mahmud, Shawn; Hazen, Melissa M; Halyabar, Olha; Hoyt, Kacie J; Han, Joseph; Grom, Alexei A; Gattorno, Marco; Ravelli, Angelo; De Benedetti, Fabrizio; Behrens, Edward M; Cron, Randy Q; Nigrovic, Peter A.
Afiliação
  • Henderson LA; Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Canna SW; UPMC Children's Hospital of Pittsburgh and University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Schulert GS; Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio.
  • Volpi S; Center for Autoinflammatory Diseases and Immunodeficiency, IRCCS Istituto Giannina Gaslini, and Università degli Studi di Genova, Genoa, Italy.
  • Lee PY; Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Kernan KF; UPMC Children's Hospital of Pittsburgh and University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Caricchio R; Temple University Hospital and Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
  • Mahmud S; University of Minnesota Medical Center and University of Minnesota School of Medicine, Minneapolis.
  • Hazen MM; Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Halyabar O; Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Hoyt KJ; Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Han J; Icahn School of Medicine at Mount Sinai, New York, New York.
  • Grom AA; Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio.
  • Gattorno M; Center for Autoinflammatory Diseases and Immunodeficiency, IRCCS Istituto Giannina Gaslini, and Università degli Studi di Genova, Genoa, Italy.
  • Ravelli A; Clinica Pediatrica e Reumatologia, IRCCS Istituto Giannina Gaslini, and Università degli Studi di Genova, Genoa, Italy.
  • De Benedetti F; Ospedale Pediatrico Bambino Gesù, Rome, Italy.
  • Behrens EM; Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Cron RQ; Children's of Alabama, University of Alabama at Birmingham, Birmingham.
  • Nigrovic PA; Boston Children's Hospital, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.
Arthritis Rheumatol ; 72(7): 1059-1063, 2020 07.
Article em En | MEDLINE | ID: mdl-32293098
ABSTRACT
Poor outcomes in COVID-19 correlate with clinical and laboratory features of cytokine storm syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy may prevent immunopathology and could help conserve limited health care resources. While studies are ongoing, extrapolating from clinical experience in cytokine storm syndromes may benefit the multidisciplinary teams caring for patients with severe COVID-19.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Síndrome da Liberação de Citocina / Anti-Inflamatórios Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Síndrome da Liberação de Citocina / Anti-Inflamatórios Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article