H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice.

Lambertz, Ruth Lydia Olga; Gerhauser, Ingo; Nehlmeier, Inga; Gärtner, Sabine; Winkler, Michael; Leist, Sarah Rebecca; Kollmus, Heike; Pöhlmann, Stefan; Schughart, Klaus

Lambertz, Ruth Lydia Olga; Gerhauser, Ingo; Nehlmeier, Inga; Gärtner, Sabine; Winkler, Michael; Leist, Sarah Rebecca; Kollmus, Heike; Pöhlmann, Stefan; Schughart, Klaus.

Afiliação

Lambertz RLO; Department of Infection Genetics, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Gerhauser I; Department of Pathology, University of Veterinary Medicine Hannover, Hannover, Germany.
Nehlmeier I; Infection Biology Unit, German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.
Gärtner S; Infection Biology Unit, German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.
Winkler M; Infection Biology Unit, German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.
Leist SR; Department of Infection Genetics, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Kollmus H; Current Address: Department of Epidemiology, University of North Carolina, Chapel Hill, USA.
Pöhlmann S; Department of Infection Genetics, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Schughart K; Infection Biology Unit, German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.

Virol J ; 17(1): 56, 2020 04 22.

Article em En | MEDLINE | ID: mdl-32321537

Assuntos

Glicoproteínas de Hemaglutininação de Vírus da Influenza/metabolismo; Vírus da Influenza A/patogenicidade; Infecções por Orthomyxoviridae/genética; Serina Endopeptidases/genética; Animais; Feminino; Células HEK293; Humanos; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Infecções por Orthomyxoviridae/imunologia; Vírus Reordenados/patogenicidade; Serina Endopeptidases/imunologia; Replicação Viral

Palavras-chave

H2 subtype; Host protease; Influenza a virus; Mouse mutant; TMPRSS2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus da Influenza A / Serina Endopeptidases / Infecções por Orthomyxoviridae / Glicoproteínas de Hemaglutininação de Vírus da Influenza Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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