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The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.
Xu, Daqian; Wang, Zheng; Xia, Yan; Shao, Fei; Xia, Weiya; Wei, Yongkun; Li, Xinjian; Qian, Xu; Lee, Jong-Ho; Du, Linyong; Zheng, Yanhua; Lv, Guishuai; Leu, Jia-Shiun; Wang, Hongyang; Xing, Dongming; Liang, Tingbo; Hung, Mien-Chie; Lu, Zhimin.
Afiliação
  • Xu D; Department of Hepatobiliary and Pancreatic Surgery and Zhejiang Provincial Key Laboratory of Pancreatic Disease of The First Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China. xudaqian@zju.edu.cn.
  • Wang Z; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. xudaqian@zju.edu.cn.
  • Xia Y; The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Shao F; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Xia W; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Wei Y; The Affiliated Hospital of Qingdao University and Qingdao Cancer Institute, Qingdao, China.
  • Li X; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Qian X; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Lee JH; CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
  • Du L; Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing, China.
  • Zheng Y; Department of Biological Sciences, Dong-A University, Busan, South Korea.
  • Lv G; Key Laboratory of Laboratory Medicine, Ministry of Education of China, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, China.
  • Leu JS; Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Wang H; International Co-operation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, Second Military Medical University, Shanghai, China.
  • Xing D; Department of Neurosurgery, Houston Methodist Research Institute, Houston, TX, USA.
  • Liang T; International Co-operation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, Second Military Medical University, Shanghai, China.
  • Hung MC; The Affiliated Hospital of Qingdao University and Qingdao Cancer Institute, Qingdao, China.
  • Lu Z; School of Life Sciences, Tsinghua University, Beijing, China.
Nature ; 580(7804): 530-535, 2020 04.
Article em En | MEDLINE | ID: mdl-32322062
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoenolpiruvato Carboxiquinase (GTP) / Carcinoma Hepatocelular / Peptídeos e Proteínas de Sinalização Intracelular / Lipogênese / Gluconeogênese / Neoplasias Hepáticas / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoenolpiruvato Carboxiquinase (GTP) / Carcinoma Hepatocelular / Peptídeos e Proteínas de Sinalização Intracelular / Lipogênese / Gluconeogênese / Neoplasias Hepáticas / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article