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Gut Microbiota and Liver Injury (I)-Acute Liver Injury.
Wu, Guangyan; Win, Sanda; Than, Tin A; Chen, Peng; Kaplowitz, Neil.
Afiliação
  • Wu G; Department of Pathophysiology, Guangdong Provincial Key Laboratory of Proteomics, School of Basic Medical Sciences, Southern Medical University, N.No 1838 Guangzhou Ave., Guangzhou, 510515, China.
  • Win S; USC Research Center for Liver Disease, Department of Medicine, Keck School of Medicine of USC, Los Angeles, CA, 90089, USA.
  • Than TA; USC Research Center for Liver Disease, Department of Medicine, Keck School of Medicine of USC, Los Angeles, CA, 90089, USA.
  • Chen P; Department of Pathophysiology, Guangdong Provincial Key Laboratory of Proteomics, School of Basic Medical Sciences, Southern Medical University, N.No 1838 Guangzhou Ave., Guangzhou, 510515, China.
  • Kaplowitz N; USC Research Center for Liver Disease, Department of Medicine, Keck School of Medicine of USC, Los Angeles, CA, 90089, USA. kaplowit@usc.edu.
Adv Exp Med Biol ; 1238: 23-37, 2020.
Article em En | MEDLINE | ID: mdl-32323178
Over the last few decades, intestinal microbial communities have been considered to play a vital role in host liver health. Acute liver injury (ALI) is the manifestation of sudden hepatic injury and arises from a variety of causes. The studies of dysbiosis in gut microbiota provide new insight into the pathogenesis of ALI. However, the relationship of gut microbiota and ALI is not well understood, and the contribution of gut microbiota to ALI has not been well characterized. In this chapter, we integrate several major pathogenic factors in ALI with the role of gut microbiota to stress the significance of gut microbiota in prevention and treatment of ALI.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Disbiose / Microbioma Gastrointestinal / Fígado / Hepatopatias Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Disbiose / Microbioma Gastrointestinal / Fígado / Hepatopatias Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article