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BRAF inhibition curtails IFN-gamma-inducible PD-L1 expression and upregulates the immunoregulatory protein galectin-1 in melanoma cells.
Górniak, Patryk; Wasylecka-Juszczynska, Maja; Lugowska, Iwona; Rutkowski, Piotr; Polak, Anna; Szydlowski, Maciej; Juszczynski, Przemyslaw.
Afiliação
  • Górniak P; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Wasylecka-Juszczynska M; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Lugowska I; Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Rutkowski P; Department of Biostatistics, Institute of Mother and Child, Warsaw, Poland.
  • Polak A; Early Phase Clinical Trial Unit, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Szydlowski M; Department of Soft Tissue/Bone Sarcoma and Melanoma, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Juszczynski P; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
Mol Oncol ; 14(8): 1817-1832, 2020 08.
Article em En | MEDLINE | ID: mdl-32330348
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação para Cima / Interferon gama / Galectina 1 / Proteínas Proto-Oncogênicas B-raf / Imunomodulação / Antígeno B7-H1 / Melanoma Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Regulação para Cima / Interferon gama / Galectina 1 / Proteínas Proto-Oncogênicas B-raf / Imunomodulação / Antígeno B7-H1 / Melanoma Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article