Fatal Chemotherapy-induced Combined Infection in a Hodgkin's Disease Patient: a Case Report.
Folia Med (Plovdiv)
; 61(4): 620-623, 2019 12 31.
Article
em En
| MEDLINE
| ID: mdl-32337875
ABSTRACT
Multimodal therapy, used for the treatment of patients with Hodgkin's disease (HD), makes them prone to life-threatening infections, attributed mainly to febrile neutropenia. Herein, we present a case report of fatal combined bacterial and viral infection in a 49-year-old female patient, subject to polychemotherapy for HD. Rapid microbiological diagnosis performed by multiplex polymerase chain reaction elucidated the causes of the infection within hours. Listeria monocytogenes was detected in both the cerebrospinal fluid and blood samples. Nasopharyngeal swabs returned positive for two swine-derived strains of influenza A virus. We aimed to emphasize the importance of these pathogens and draw attention to their association in the aetiology of infections among patients receiving chemotherapy. In conclusion, better surveillance is needed to improve the early diagnosis of infectious complications in these patients.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença de Hodgkin
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Listeriose
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Listeria monocytogenes
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Antineoplásicos
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Female
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Humans
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Middle aged
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article