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Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas.
Krishnan, Aswini; Berthelet, Jean; Renaud, Emilie; Rosigkeit, Sebastian; Distler, Ute; Stawiski, Eric; Wang, Jing; Modrusan, Zora; Fiedler, Marc; Bienz, Mariann; Tenzer, Stefan; Schad, Arno; Roth, Wilfried; Thiede, Bernd; Seshagiri, Somasekar; Musholt, Thomas J; Rajalingam, Krishnaraj.
Afiliação
  • Krishnan A; Cell Biology Unit, University Medical Center of the Johannes Gutenberg University Mainz, 55131, Mainz, Germany.
  • Berthelet J; Cell Biology Unit, University Medical Center of the Johannes Gutenberg University Mainz, 55131, Mainz, Germany.
  • Renaud E; Cell Biology Unit, University Medical Center of the Johannes Gutenberg University Mainz, 55131, Mainz, Germany.
  • Rosigkeit S; Cell Biology Unit, University Medical Center of the Johannes Gutenberg University Mainz, 55131, Mainz, Germany.
  • Distler U; Institute of Immunology, University Medical Center of the Johannes Gutenberg University Mainz, 55131, Mainz, Germany.
  • Stawiski E; MedGenome, Inc., Foster City, CA, USA.
  • Wang J; MedGenome, Inc., Foster City, CA, USA.
  • Modrusan Z; Molecular Biology Department, Genentech, Inc., South San Francisco, CA, USA.
  • Fiedler M; MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
  • Bienz M; MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
  • Tenzer S; Institute of Immunology, University Medical Center of the Johannes Gutenberg University Mainz, 55131, Mainz, Germany.
  • Schad A; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
  • Roth W; Institute of Pathology, University Medical Center Mainz, Mainz, Germany.
  • Thiede B; Department of Biosciences, University of Oslo, 0371, Oslo, Norway.
  • Seshagiri S; Molecular Biology Department, Genentech, Inc., South San Francisco, CA, USA.
  • Musholt TJ; SciGenom Research Foundation, Bangalore, India.
  • Rajalingam K; Endocrine Surgery Section, Department of General Visceral and Transplantation Surgery, University Medicine, Mainz, Germany.
Nat Commun ; 11(1): 2056, 2020 04 28.
Article em En | MEDLINE | ID: mdl-32345963
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Glândula Tireoide / Proteínas / Proteínas de Fusão Oncogênica / Proteínas Proto-Oncogênicas c-ret / Proteogenômica / Câncer Papilífero da Tireoide Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Glândula Tireoide / Proteínas / Proteínas de Fusão Oncogênica / Proteínas Proto-Oncogênicas c-ret / Proteogenômica / Câncer Papilífero da Tireoide Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article