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Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors.
Morgen, Michael; Steimbach, Raphael R; Géraldy, Magalie; Hellweg, Lars; Sehr, Peter; Ridinger, Johannes; Witt, Olaf; Oehme, Ina; Herbst-Gervasoni, Corey J; Osko, Jeremy D; Porter, Nicholas J; Christianson, David W; Gunkel, Nikolas; Miller, Aubry K.
Afiliação
  • Morgen M; Cancer Drug Development Group, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Steimbach RR; Cancer Drug Development Group, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Géraldy M; Faculty of Biosciences, University of Heidelberg, 69120, Heidelberg, Germany.
  • Hellweg L; Cancer Drug Development Group, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Sehr P; Cancer Drug Development Group, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Ridinger J; Chemical Biology Core Facility, European Molecular Biology Laboratory (EMBL), 69117, Heidelberg, Germany.
  • Witt O; Hopp Children's Cancer Center Heidelberg (KiTZ), 69120, Heidelberg, Germany.
  • Oehme I; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
  • Herbst-Gervasoni CJ; Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, 69120, Heidelberg, Germany.
  • Osko JD; Hopp Children's Cancer Center Heidelberg (KiTZ), 69120, Heidelberg, Germany.
  • Porter NJ; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.
  • Christianson DW; Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, 69120, Heidelberg, Germany.
  • Gunkel N; German Cancer Consortium (DKTK), 69120, Heidelberg, Germany.
  • Miller AK; Hopp Children's Cancer Center Heidelberg (KiTZ), 69120, Heidelberg, Germany.
ChemMedChem ; 15(13): 1163-1174, 2020 07 03.
Article em En | MEDLINE | ID: mdl-32348628
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Desenho de Fármacos / Inibidores de Histona Desacetilases / Desacetilase 6 de Histona / Ácidos Hidroxâmicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Desenho de Fármacos / Inibidores de Histona Desacetilases / Desacetilase 6 de Histona / Ácidos Hidroxâmicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article