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Antibody responses to SARS-CoV-2 in patients with COVID-19.
Long, Quan-Xin; Liu, Bai-Zhong; Deng, Hai-Jun; Wu, Gui-Cheng; Deng, Kun; Chen, Yao-Kai; Liao, Pu; Qiu, Jing-Fu; Lin, Yong; Cai, Xue-Fei; Wang, De-Qiang; Hu, Yuan; Ren, Ji-Hua; Tang, Ni; Xu, Yin-Yin; Yu, Li-Hua; Mo, Zhan; Gong, Fang; Zhang, Xiao-Li; Tian, Wen-Guang; Hu, Li; Zhang, Xian-Xiang; Xiang, Jiang-Lin; Du, Hong-Xin; Liu, Hua-Wen; Lang, Chun-Hui; Luo, Xiao-He; Wu, Shao-Bo; Cui, Xiao-Ping; Zhou, Zheng; Zhu, Man-Man; Wang, Jing; Xue, Cheng-Jun; Li, Xiao-Feng; Wang, Li; Li, Zhi-Jie; Wang, Kun; Niu, Chang-Chun; Yang, Qing-Jun; Tang, Xiao-Jun; Zhang, Yong; Liu, Xia-Mao; Li, Jin-Jing; Zhang, De-Chun; Zhang, Fan; Liu, Ping; Yuan, Jun; Li, Qin; Hu, Jie-Li; Chen, Juan.
Afiliação
  • Long QX; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Liu BZ; Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing, China.
  • Deng HJ; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Wu GC; Chongqing University Three Gorges Hospital, Chongqing, China.
  • Deng K; Chongqing Three Gorges Central Hospital, Chongqing, China.
  • Chen YK; The Third Hospital Affiliated to Chongqing Medical University, Chongqing, China.
  • Liao P; Division of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, China.
  • Qiu JF; Laboratory Department, Chongqing People's Hospital, Chongqing, China.
  • Lin Y; School of Public Health and Management, Chongqing Medical University, Chongqing, China.
  • Cai XF; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Wang DQ; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Hu Y; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Ren JH; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Tang N; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Xu YY; Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Chongqing Medical University, Chongqing, China.
  • Yu LH; Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing, China.
  • Mo Z; Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing, China.
  • Gong F; Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing, China.
  • Zhang XL; Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing, China.
  • Tian WG; Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing, China.
  • Hu L; Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing, China.
  • Zhang XX; Yongchuan Hospital Affiliated to Chongqing Medical University, Chongqing, China.
  • Xiang JL; Chongqing University Three Gorges Hospital, Chongqing, China.
  • Du HX; Chongqing Three Gorges Central Hospital, Chongqing, China.
  • Liu HW; Chongqing University Three Gorges Hospital, Chongqing, China.
  • Lang CH; Chongqing Three Gorges Central Hospital, Chongqing, China.
  • Luo XH; Chongqing University Three Gorges Hospital, Chongqing, China.
  • Wu SB; Chongqing Three Gorges Central Hospital, Chongqing, China.
  • Cui XP; Chongqing University Three Gorges Hospital, Chongqing, China.
  • Zhou Z; Chongqing Three Gorges Central Hospital, Chongqing, China.
  • Zhu MM; Chongqing University Three Gorges Hospital, Chongqing, China.
  • Wang J; Chongqing Three Gorges Central Hospital, Chongqing, China.
  • Xue CJ; Chongqing University Three Gorges Hospital, Chongqing, China.
  • Li XF; Chongqing Three Gorges Central Hospital, Chongqing, China.
  • Wang L; Chongqing University Three Gorges Hospital, Chongqing, China.
  • Li ZJ; Chongqing Three Gorges Central Hospital, Chongqing, China.
  • Wang K; Chongqing University Three Gorges Hospital, Chongqing, China.
  • Niu CC; Chongqing Three Gorges Central Hospital, Chongqing, China.
  • Yang QJ; Chongqing University Three Gorges Hospital, Chongqing, China.
  • Tang XJ; Chongqing Three Gorges Central Hospital, Chongqing, China.
  • Zhang Y; The Third Hospital Affiliated to Chongqing Medical University, Chongqing, China.
  • Liu XM; Division of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, China.
  • Li JJ; Division of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, China.
  • Zhang DC; Division of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, China.
  • Zhang F; Division of Infectious Diseases, Chongqing Public Health Medical Center, Chongqing, China.
  • Liu P; Laboratory Department, Chongqing People's Hospital, Chongqing, China.
  • Yuan J; Laboratory Department, Chongqing People's Hospital, Chongqing, China.
  • Li Q; Laboratory Department, Chongqing People's Hospital, Chongqing, China.
  • Hu JL; Laboratory Department, Chongqing People's Hospital, Chongqing, China.
  • Chen J; School of Public Health and Management, Chongqing Medical University, Chongqing, China.
Nat Med ; 26(6): 845-848, 2020 06.
Article em En | MEDLINE | ID: mdl-32350462
We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG and IgM occurred simultaneously or sequentially. Both IgG and IgM titers plateaued within 6 days after seroconversion. Serological testing may be helpful for the diagnosis of suspected patients with negative RT-PCR results and for the identification of asymptomatic infections.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Betacoronavirus / Anticorpos Antivirais / Formação de Anticorpos Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por Coronavirus / Betacoronavirus / Anticorpos Antivirais / Formação de Anticorpos Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article