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HER2 antibody-drug conjugate controls growth of breast cancer brain metastases in hematogenous xenograft models, with heterogeneous blood-tumor barrier penetration unlinked to a passive marker.
Gril, Brunilde; Wei, Debbie; Zimmer, Alexandra S; Robinson, Christina; Khan, Imran; Difilippantonio, Simone; Overstreet, Michael G; Steeg, Patricia S.
Afiliação
  • Gril B; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Wei D; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Zimmer AS; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Robinson C; Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland.
  • Khan I; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
  • Difilippantonio S; Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland.
  • Overstreet MG; Oncology R&D, AstraZeneca, Gaithersburg, Maryland.
  • Steeg PS; Women's Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.
Neuro Oncol ; 22(11): 1625-1636, 2020 11 26.
Article em En | MEDLINE | ID: mdl-32386414
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Neoplasias da Mama Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Neoplasias da Mama Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article