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Synthesis and biological evaluation of triazolyl-substituted benzyloxyacetohydroxamic acids as LpxC inhibitors.
Hoff, Katharina; Mielniczuk, Sebastian; Agoglitta, Oriana; Iorio, Maria Teresa; Caldara, Manlio; Bülbül, Emre F; Melesina, Jelena; Sippl, Wolfgang; Holl, Ralph.
Afiliação
  • Hoff K; Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems.
  • Mielniczuk S; Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems.
  • Agoglitta O; Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems; NRW Graduate School of Chemistry, University of Münster, Germany; Institute of Pharmaceutical and Medicin
  • Iorio MT; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstr. 48, 48149 Münster, Germany.
  • Caldara M; Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.
  • Bülbül EF; Institute of Pharmacy, Martin Luther University of Halle-Wittenberg, Wolfgang-Langenbeck Str. 4, 06120 Halle (Saale), Germany.
  • Melesina J; Institute of Pharmacy, Martin Luther University of Halle-Wittenberg, Wolfgang-Langenbeck Str. 4, 06120 Halle (Saale), Germany.
  • Sippl W; Institute of Pharmacy, Martin Luther University of Halle-Wittenberg, Wolfgang-Langenbeck Str. 4, 06120 Halle (Saale), Germany.
  • Holl R; Institute of Organic Chemistry, University of Hamburg, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany; German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems. Electronic address: ralph.holl@chemie.uni-hamburg.de.
Bioorg Med Chem ; 28(13): 115529, 2020 07 01.
Article em En | MEDLINE | ID: mdl-32386952
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Triazóis / Inibidores Enzimáticos / Amidoidrolases / Ácidos Hidroxâmicos / Antibacterianos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Triazóis / Inibidores Enzimáticos / Amidoidrolases / Ácidos Hidroxâmicos / Antibacterianos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article