Vitamin D Supplementation Rescues Aberrant NF-&#954;B Pathway Activation and Partially Ameliorates Rett Syndrome Phenotypes in <i>Mecp2</i> Mutant Mice.

Ribeiro, Mayara C; Moore, Seth M; Kishi, Noriyuki; Macklis, Jeffrey D; MacDonald, Jessica L

Vitamin D Supplementation Rescues Aberrant NF-κB Pathway Activation and Partially Ameliorates Rett Syndrome Phenotypes in Mecp2 Mutant Mice.

Ribeiro, Mayara C; Moore, Seth M; Kishi, Noriyuki; Macklis, Jeffrey D; MacDonald, Jessica L.

Afiliação

Ribeiro MC; Department of Biology, Program in Neuroscience, Syracuse University, Syracuse, NY 13244.
Moore SM; Department of Biology, Program in Neuroscience, Syracuse University, Syracuse, NY 13244.
Kishi N; Department of Stem Cell and Regenerative Biology, and Center for Brain Science, Harvard University, Cambridge, MA 02138.
Macklis JD; Department of Stem Cell and Regenerative Biology, and Center for Brain Science, Harvard University, Cambridge, MA 02138 jemacdon@syr.edu jeffrey_macklis@harvard.edu.
MacDonald JL; Department of Biology, Program in Neuroscience, Syracuse University, Syracuse, NY 13244 jemacdon@syr.edu jeffrey_macklis@harvard.edu.

eNeuro ; 7(3)2020.

Article em En | MEDLINE | ID: mdl-32393583

Assuntos

Síndrome de Rett; Animais; Suplementos Nutricionais; Modelos Animais de Doenças; Feminino; Humanos; Masculino; Proteína 2 de Ligação a Metil-CpG/genética; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; NF-kappa B; Fenótipo; Síndrome de Rett/tratamento farmacológico; Síndrome de Rett/genética; Vitamina D

Palavras-chave

NF-κB; Rett syndrome; epigenetics; neocortex; neuronal morphology; vitamin D

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Rett Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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