Soybean-derived miRNAs specifically inhibit proliferation and stimulate apoptosis of human colonic Caco-2 cancer cells but not normal mucosal cells in culture.

Liu, Juncheng; Wang, Fang; Weng, Zebin; Sui, Xiaonan; Fang, Yong; Tang, Xiaozhi; Shen, Xinchun

Liu, Juncheng; Wang, Fang; Weng, Zebin; Sui, Xiaonan; Fang, Yong; Tang, Xiaozhi; Shen, Xinchun.

Afiliação

Liu J; College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210046, China.
Wang F; College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210046, China.
Weng Z; Basic Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Sui X; College of Food Science, Northeast Agricultural University, Harbin 150030, China.
Fang Y; College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210046, China.
Tang X; College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210046, China.
Shen X; College of Food Science and Engineering, Collaborative Innovation Center for Modern Grain Circulation and Safety, Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing 210046, China. Electronic address: shenxinchun@nufe.edu.cn.

Genomics ; 112(5): 2949-2958, 2020 09.

Article em En | MEDLINE | ID: mdl-32407773

Assuntos

Neoplasias do Colo/genética; Glycine max/genética; MicroRNAs/fisiologia; RNA de Plantas/fisiologia; Apoptose; Células CACO-2; Linhagem Celular; Proliferação de Células; Neoplasias do Colo/metabolismo; Neoplasias do Colo/patologia; Progressão da Doença; Humanos; Mucosa Intestinal/citologia; Fator 1 de Transcrição de Linfócitos T/genética; Fator 1 de Transcrição de Linfócitos T/metabolismo

Palavras-chave

Bioinformatics analysis; Caco-2; Gma-miR159a; Soybean; TCF7; microRNAs

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glycine max / Neoplasias do Colo / RNA de Plantas / MicroRNAs Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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