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Complete neural stem cell (NSC) neuronal differentiation requires a branched chain amino acids-induced persistent metabolic shift towards energy metabolism.
Bifari, Francesco; Dolci, Sissi; Bottani, Emanuela; Pino, Annachiara; Di Chio, Marzia; Zorzin, Stefania; Ragni, Maurizio; Zamfir, Raluca Georgiana; Brunetti, Dario; Bardelli, Donatella; Delfino, Pietro; Cattaneo, Maria Grazia; Bordo, Roberta; Tedesco, Laura; Rossi, Fabio; Bossolasco, Patrizia; Corbo, Vincenzo; Fumagalli, Guido; Nisoli, Enzo; Valerio, Alessandra; Decimo, Ilaria.
Afiliação
  • Bifari F; Laboratory of Cell Metabolism and Regenerative Medicine, Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy. Electronic address: francesco.bifari@unimi.it.
  • Dolci S; Department of Diagnostics and Public Health, Section of Pharmacology, University of Verona, Verona, Italy.
  • Bottani E; Department of Diagnostics and Public Health, Section of Pharmacology, University of Verona, Verona, Italy; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
  • Pino A; Department of Diagnostics and Public Health, Section of Pharmacology, University of Verona, Verona, Italy.
  • Di Chio M; Department of Diagnostics and Public Health, Section of Pharmacology, University of Verona, Verona, Italy.
  • Zorzin S; Department of Diagnostics and Public Health, Section of Pharmacology, University of Verona, Verona, Italy.
  • Ragni M; Center for Study and Research on Obesity, Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.
  • Zamfir RG; Department of Diagnostics and Public Health, Section of Pharmacology, University of Verona, Verona, Italy.
  • Brunetti D; Center for Study and Research on Obesity, Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.
  • Bardelli D; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.
  • Delfino P; Department of Diagnostics and Public Health, Section of Pathological Anatomy, University of Verona, Verona, Italy.
  • Cattaneo MG; Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.
  • Bordo R; Laboratory of Cell Metabolism and Regenerative Medicine, Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.
  • Tedesco L; Center for Study and Research on Obesity, Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.
  • Rossi F; Center for Study and Research on Obesity, Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.
  • Bossolasco P; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.
  • Corbo V; Department of Diagnostics and Public Health, Section of Pathological Anatomy, University of Verona, Verona, Italy.
  • Fumagalli G; Department of Diagnostics and Public Health, Section of Pharmacology, University of Verona, Verona, Italy.
  • Nisoli E; Center for Study and Research on Obesity, Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy. Electronic address: enzo.nisoli@unimi.it.
  • Valerio A; Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
  • Decimo I; Department of Diagnostics and Public Health, Section of Pharmacology, University of Verona, Verona, Italy. Electronic address: ilaria.decimo@univr.it.
Pharmacol Res ; 158: 104863, 2020 08.
Article em En | MEDLINE | ID: mdl-32407957
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Metabolismo Energético / Células-Tronco Neurais / Aminoácidos de Cadeia Ramificada Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Metabolismo Energético / Células-Tronco Neurais / Aminoácidos de Cadeia Ramificada Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article