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Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 Inhibition.
Li, Ming; Phua, Zheng Yen; Xi, Yu; Xu, Zhujun; Nyantakyi, Samuel A; Li, Wei; Jackson, Mary; Wong, Ming Wah; Lam, Yulin; Chng, Shu Sin; Go, Mei Lin; Dick, Thomas.
Afiliação
  • Li M; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 117599 Singapore.
  • Phua ZY; Department of Chemistry, Faculty of Science, National University of Singapore, 117543 Singapore.
  • Xi Y; Department of Chemistry, Faculty of Science, National University of Singapore, 117543 Singapore.
  • Xu Z; Department of Chemistry, Faculty of Science, National University of Singapore, 117543 Singapore.
  • Nyantakyi SA; Department of Pharmacy, Faculty of Science, National University of Singapore, 117559 Singapore.
  • Li W; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, United States.
  • Jackson M; Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523-1682, United States.
  • Wong MW; Department of Chemistry, Faculty of Science, National University of Singapore, 117543 Singapore.
  • Lam Y; Department of Chemistry, Faculty of Science, National University of Singapore, 117543 Singapore.
  • Chng SS; Department of Chemistry, Faculty of Science, National University of Singapore, 117543 Singapore.
  • Go ML; Singapore Centre for Environmental Life Science Engineering (SCELSE), National University of Singapore, 117543 Singapore.
  • Dick T; Department of Pharmacy, Faculty of Science, National University of Singapore, 117559 Singapore.
ACS Infect Dis ; 6(7): 1882-1893, 2020 07 10.
Article em En | MEDLINE | ID: mdl-32413266
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mycobacterium tuberculosis / Ácidos Micólicos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mycobacterium tuberculosis / Ácidos Micólicos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article