The dynamic landscape of <i>BRCA1</i> reversion mutations from indel to SNV in a patient with ovarian cancer treated with PARP-inhibitors and immunotherapy.

Jacob, Saya L; Kiedrowski, Lesli A; Chae, Young K

The dynamic landscape of BRCA1 reversion mutations from indel to SNV in a patient with ovarian cancer treated with PARP-inhibitors and immunotherapy.

Jacob, Saya L; Kiedrowski, Lesli A; Chae, Young K.

Afiliação

Jacob SL; Northwestern University Feinberg School of Medicine, Chicago IL, USA.
Kiedrowski LA; Guardant Health, Redwood City, CA, USA.
Chae YK; Northwestern University Feinberg School of Medicine, Chicago IL, USA.

Heliyon ; 6(5): e03841, 2020 May.

Article em En | MEDLINE | ID: mdl-32420470

Palavras-chave

Biological sciences; Cancer research; Clinical research; Genetics; Molecular biology; Molecular genetics; Next generation sequencing; Oncology; Organ system; Pathophysiology; Pharmaceutical science; Proteins; Translational science

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article