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TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling.
Goldsmith, Jason R; Spitofsky, Nina; Zamani, Ali; Hood, Ryan; Boggs, Amanda; Li, Xinyuan; Li, Mingyue; Reiner, Elizabeth; Ayyaz, Arshad; Etwebi, Zienab; Lu, Ling; Rivera Guzman, Javier; Bou-Dargham, Mayassa J; Cathoupolis, Terry; Hakonarson, Hakon; Sun, Honghong; Wrana, Jeffrey L; Gonzalez, Michael V; Chen, Youhai H.
Afiliação
  • Goldsmith JR; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. goldsj@pennmedicine.upenn.edu.
  • Spitofsky N; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Zamani A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Hood R; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Boggs A; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Li X; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Li M; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Reiner E; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Ayyaz A; University of Pikeville-Kentucky School of Osteopathic Medicine, Pikeville, KY, 41501, USA.
  • Etwebi Z; Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.
  • Lu L; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Rivera Guzman J; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Bou-Dargham MJ; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Cathoupolis T; Department of Biology, University of Maryland Baltimore College, Baltimore, MD, 21250, USA.
  • Hakonarson H; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Sun H; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Wrana JL; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Gonzalez MV; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Chen YH; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Nat Commun ; 11(1): 2591, 2020 05 22.
Article em En | MEDLINE | ID: mdl-32444641

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-akt / Proteínas Reguladoras de Apoptose / Microbioma Gastrointestinal / Intestinos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-akt / Proteínas Reguladoras de Apoptose / Microbioma Gastrointestinal / Intestinos Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article