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[Risk factors and clinical features of hospital-associated venous thromboembolism].
Shao, X; Si, C Z; Zhen, K Y; Zhang, Z; Wang, J; Wang, D Y; Lei, J P; Wan, J; Xie, W M; Zhai, Z G; Wang, C.
Afiliação
  • Shao X; China-Japan Friendship Clinical Medical College, Beijing University of Chinese Medicine, Beijing 100029, China.
  • Si CZ; Information Center, China-Japan Friendship Hospital, Beijing 100029, China.
  • Zhen KY; Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China.
  • Zhang Z; Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
  • Wang J; Department of Pulmonary and Critical Care Medicine Center of Respiratory Medicine, Beijing Hospital, Beijing 100730, China.
  • Wang DY; Data and Project Management Unit, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China.
  • Lei JP; Data and Project Management Unit, Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China.
  • Wan J; Department of Pulmonary and Critical Care Medicine Center of Respiratory Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing 100029, China.
  • Xie WM; Department of Pulmonary and Critical Care Medicine Center of Respiratory Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing 100029, China.
  • Zhai ZG; Department of Pulmonary and Critical Care Medicine Center of Respiratory Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing 100029, China.
  • Wang C; Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Zhonghua Yi Xue Za Zhi ; 100(20): 1539-1543, 2020 May 26.
Article em Zh | MEDLINE | ID: mdl-32450641
Objective: To investigate the clinical features and risk factors of hospital-associated venous thromboembolism (VTE). Methods: The study enrolled acute VTE patients admitted into China-Japan Friendship Hospital from January 1, 2017 to December 31, 2017. The hospital-associated VTE (HA-VTE) group and the community-associated VTE (CA-VTE) group were classified according to whether the VTE occurred during hospitalization or within a 90-day period of admission to hospital (including inpatient with at least two days of hospital stay or a surgical procedure under general or regional anaesthesia). Differences in clinical features, risk factors, and mortality rate were compared between the two groups. Results: A total of 437 patients with acute VTE were analyzed in the study. Among them, 266 patients were HA-VTE, 171 patients were CA-VTE. Patients in the CA-VTE group were more likely to have varicose veins, sedentary, long-distance travel, and patients in the HA-VTE group were more complicated with recent surgery (<1 month), bed rest, active malignant tumor, acute infections, acute cerebral infarction, fracture, central venous catheter (P<0.05). The CA-VTE group had more clinical symptoms such as lower extremity pain, dyspnea, chest pain and chest tightness (P<0.05). HA-VTE patients had less clinical symptoms but were more severe than the CA-VTE patients, with more sudden deaths (0 vs 3.4%, P=0.035). Among HA-VTE patients, 92.8% experienced VTE during hospitalization or within 1 month of the preceding hospital encounter, with a 13-day median time to VTE. The all-cause mortality rate was higher for HA-VTE group than CA-VTE group (8.3% vs 1.2%, P<0.001), and the in-hospital VTE was more common compared to VTE diagnosed post-discharge (12.2% vs 3.4%, P<0.001). Conclusions: More than half events of VTE are related to recent hospitalizations. HA-VTE has different risk factors from CA-VTE, combined with fewer clinical symptoms but higher all-cause mortality rate. More attention about VTE should be paid to hospitalized patients to reduce the incidence of HA-VTE events.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tromboembolia Venosa Tipo de estudo: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: Asia Idioma: Zh Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tromboembolia Venosa Tipo de estudo: Etiology_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: Asia Idioma: Zh Ano de publicação: 2020 Tipo de documento: Article