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Activation of Mitochondrial 2-Oxoglutarate Dehydrogenase by Cocarboxylase in Human Lung Adenocarcinoma Cells A549 Is p53/p21-Dependent and Impairs Cellular Redox State, Mimicking the Cisplatin Action.
Bunik, Victoria I; Aleshin, Vasily A; Zhou, Xiaoshan; Tabakov, Vyacheslav Yu; Karlsson, Anna.
Afiliação
  • Bunik VI; A.N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
  • Aleshin VA; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991 Moscow, Russia.
  • Zhou X; Department of Biochemistry, Sechenov University, 119991 Moscow, Russia.
  • Tabakov VY; A.N. Belozersky Institute of Physicochemical Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.
  • Karlsson A; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, 119991 Moscow, Russia.
Int J Mol Sci ; 21(11)2020 May 26.
Article em En | MEDLINE | ID: mdl-32466567
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiamina Pirofosfato / Adenocarcinoma / Proteína Supressora de Tumor p53 / Inibidor de Quinase Dependente de Ciclina p21 / Complexo Cetoglutarato Desidrogenase / Neoplasias Pulmonares Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiamina Pirofosfato / Adenocarcinoma / Proteína Supressora de Tumor p53 / Inibidor de Quinase Dependente de Ciclina p21 / Complexo Cetoglutarato Desidrogenase / Neoplasias Pulmonares Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article