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The use of vitamin D in preventing post-thyroidectomy hypocalcemia: An endocrinologist survey study.
Pinardo, Heinrich; Rubin, Samuel J; Hashemi, Sean; DePietro, Joseph; Pearce, Elizabeth N; Ananthakrishnan, Sonia; Alexanian, Sara M; Steenkamp, Devin W; Noordzij, Jacob Pieter.
Afiliação
  • Pinardo H; Department of Otolaryngology-Head & Neck Surgery, Boston Medical Center, Boston, MA, USA.
  • Rubin SJ; Department of Otolaryngology-Head & Neck Surgery, Boston Medical Center, Boston, MA, USA.
  • Hashemi S; Department of Otolaryngology-Head & Neck Surgery, Boston Medical Center, Boston, MA, USA.
  • DePietro J; Department of Otolaryngology-Head & Neck Surgery, Boston Medical Center, Boston, MA, USA.
  • Pearce EN; Department of Medicine, Section of Endocrinology, Diabetes, Nutrition & Weight Management, Boston Medical Center, Boston, MA, USA.
  • Ananthakrishnan S; Department of Medicine, Section of Endocrinology, Diabetes, Nutrition & Weight Management, Boston Medical Center, Boston, MA, USA.
  • Alexanian SM; Department of Medicine, Section of Endocrinology, Diabetes, Nutrition & Weight Management, Boston Medical Center, Boston, MA, USA.
  • Steenkamp DW; Department of Medicine, Section of Endocrinology, Diabetes, Nutrition & Weight Management, Boston Medical Center, Boston, MA, USA.
  • Noordzij JP; Department of Otolaryngology-Head & Neck Surgery, Boston Medical Center, Boston, MA, USA.
Clin Endocrinol (Oxf) ; 93(5): 598-604, 2020 11.
Article em En | MEDLINE | ID: mdl-32469425
OBJECTIVE: To evaluate the use of preoperative vitamin D levels and postoperative vitamin D supplementation among endocrinologists for the prevention of post-thyroidectomy hypocalcaemia. METHODS: Endocrinologist members of the American Thyroid Association (ATA) were contacted via email to complete a 21-question survey, which included both questions about demographic information, and preventing and managing postoperative hypocalcaemia after thyroidectomy. Univariate and multivariate analysis was performed to determine the respondents' use of preoperative vitamin D levels, dose and duration of preoperative vitamin D repletion, decision to delay surgery for low vitamin D levels in the case of a benign or malignant disease, and routine prescription of postoperative calcium or vitamin D supplementation. RESULTS: 225 endocrinologists who were ATA members responded to the questionnaire. When compared to endocrinologists practicing in other countries, those that practice in the United States were 2.5 times more likely to check preoperative vitamin D levels (95% CI[1.404, 4.535], P = .002), significantly more likely to replete vitamin D deficient patients with high-dose vitamin D (ie ≥50K IU/week), 4.458 times more likely to prescribe prophylactic supplemental calcium (95% CI[2.446, 8.126]; P < .0001) and 3.48 more likely to prescribe supplemental vitamin D (95% CI [1.906, 6.355]; P < .0001). Endocrinologists who have been in practice for >10 years were also 1.915 times more likely to prescribe supplemental vitamin D (95% CI (1.080, 3.395); P = .0263). Physicians that treat >50 thyroidectomy cases/year were 2.083 more likely to recommend a vitamin D repletion duration of >1 month than those that treat ≤50 cases/year ([1.036, 4.190], P = .0395). Lastly, if the patient has low preoperative vitamin D levels, 47.05% of respondents chose to delay surgery in a benign disease, while only 11.61% of respondents would do so in a case of malignant disease. CONCLUSIONS: Approximately one-half of surveyed endocrinologists reported using preoperative vitamin D levels to assess a patient's risk for post-thyroidectomy hypocalcaemia. Endocrinologists practicing in the United States, compared to those practicing in other countries, were more likely to both test for preoperative vitamin D levels and to recommend prophylactic post-thyroidectomy calcium and vitamin D supplementation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hipocalcemia Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hipocalcemia Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article