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Biological and clinical characteristics of gene carriers far from predicted onset in the Huntington's disease Young Adult Study (HD-YAS): a cross-sectional analysis.
Scahill, Rachael I; Zeun, Paul; Osborne-Crowley, Katherine; Johnson, Eileanoir B; Gregory, Sarah; Parker, Christopher; Lowe, Jessica; Nair, Akshay; O'Callaghan, Claire; Langley, Christelle; Papoutsi, Marina; McColgan, Peter; Estevez-Fraga, Carlos; Fayer, Kate; Wellington, Henny; Rodrigues, Filipe B; Byrne, Lauren M; Heselgrave, Amanda; Hyare, Harpreet; Sampaio, Cristina; Zetterberg, Henrik; Zhang, Hui; Wild, Edward J; Rees, Geraint; Robbins, Trevor W; Sahakian, Barbara J; Langbehn, Douglas; Tabrizi, Sarah J.
Afiliação
  • Scahill RI; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • Zeun P; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • Osborne-Crowley K; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK; Division of Equity, Diversity and Inclusion, University of New South Wales, Sydney, NSW, Australia.
  • Johnson EB; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • Gregory S; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • Parker C; Department of Computer Science and Centre for Medical Image Computing, University College London, London, UK.
  • Lowe J; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • Nair A; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK; Max Planck University College London Centre for Computational Psychiatry and Ageing Research, UCL Queen Square Institute of Neurology, London, UK.
  • O'Callaghan C; Department of Psychiatry and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK; Brain and Mind Centre, University of Sydney, Sydney, NSW, Australia.
  • Langley C; Department of Psychiatry and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.
  • Papoutsi M; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • McColgan P; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • Estevez-Fraga C; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • Fayer K; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • Wellington H; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK; Dementia Research Institute at University College London, London, UK.
  • Rodrigues FB; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • Byrne LM; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • Heselgrave A; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK; Dementia Research Institute at University College London, London, UK.
  • Hyare H; Department of Brain Repair and Rehabilitation, University College London Institute of Neurology, London, UK.
  • Sampaio C; CHDI Foundation, Princeton, NJ, USA; Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Lisbon, Portugal.
  • Zetterberg H; Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London, UK; Dementia Research Institute at University College London, London, UK; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden; Department of Psychiatr
  • Zhang H; Department of Computer Science and Centre for Medical Image Computing, University College London, London, UK.
  • Wild EJ; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK.
  • Rees G; University College London Institute of Cognitive Neuroscience, University College London, London, UK.
  • Robbins TW; Department of Psychology and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.
  • Sahakian BJ; Department of Psychiatry and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.
  • Langbehn D; Department of Psychiatry, University of Iowa, Iowa City, IA, USA.
  • Tabrizi SJ; Huntington's Disease Centre, Department of Neurodegenerative disease, UCL Queen Square Institute of Neurology, University College London, London, UK; Dementia Research Institute at University College London, London, UK. Electronic address: s.tabrizi@ucl.ac.uk.
Lancet Neurol ; 19(6): 502-512, 2020 06.
Article em En | MEDLINE | ID: mdl-32470422
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Huntington Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male País/Região como assunto: Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Huntington Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male País/Região como assunto: Europa Idioma: En Ano de publicação: 2020 Tipo de documento: Article