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[The effects of prenatal radiation of mobile phones on white matter in cerebellum of rat offspring].
Yang, Mei-Li; Hong, Shan-Yan; Huang, Hong-Hong; Lyu, Guo-Rong; Wang, Ling-Xing.
Afiliação
  • Yang ML; Department of Neurology.
  • Hong SY; Department of Neurology.
  • Huang HH; Department of Neurology.
  • Lyu GR; Department of Ultrasound, the Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000.
  • Wang LX; Department of Clinical Medicine, Quanzhou Medical College, Quanzhou 362000, China.
Zhongguo Ying Yong Sheng Li Xue Za Zhi ; 36(1): 77-81, 2020 Jan 28.
Article em Zh | MEDLINE | ID: mdl-32476377
OBJECTIVE: To evaluate the effects of prenatal radiation of 850~1 900 MHz mobile phone on white matter in cerebellum of adult rat offspring. METHODS: Pregnant rats were randomly divided into short term maternal radiation group, long term maternal radiation group and control group. Rats in short term and long term maternal radiation group were exposed to 6 h/d and 24 h/d mobile phone radiation during 1-17 days of pregnancy, respectively. The cerebellums of offspring rats at the age of 3 month(n=8)were taken. Cell morphology in cerebellum was studied by hematoxylin-eosin (HE) staining. The expressions of myelin basic protein (MBP), neurofilament-L (NF-L) and glial fibrillary acidic protein (GFAP) in cerebellum of rat offspring were detected by immunohistochemistry and Western blot. RESULTS: Compared to control group, the morphological changes of purkinje cells in cerebellum were obvious in rat offspring of short term and long term maternal radiation group. Compared to control group, decreased MBP and NF-L expressions and increased GFAP expression were observed in long term maternal radiation group(all P<0.05). Compared to short term radiation group, the expressions of MBP and NF-L were down-regulated (all P<0.05) and the expression of GFAP was up- regulated(P<0.05) in long term radiation group. CONCLUSION: Prenatal mobile phone radiation might lead to the damage of myelin and axon with activity of astrocytes in cerebellum of male rat offspring, which is related to the extent of radiation.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Cerebelo / Telefone Celular / Radiação Eletromagnética / Substância Branca Limite: Animals / Pregnancy Idioma: Zh Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Tardios da Exposição Pré-Natal / Cerebelo / Telefone Celular / Radiação Eletromagnética / Substância Branca Limite: Animals / Pregnancy Idioma: Zh Ano de publicação: 2020 Tipo de documento: Article