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Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation.
Azazmeh, Narmen; Assouline, Benjamin; Winter, Eitan; Ruppo, Shmuel; Nevo, Yuval; Maly, Alexander; Meir, Karen; Witkiewicz, Agnieszka K; Cohen, Jonathan; Rizou, Sophia V; Pikarsky, Eli; Luxenburg, Chen; Gorgoulis, Vassilis G; Ben-Porath, Ittai.
Afiliação
  • Azazmeh N; Department of Developmental Biology and Cancer Research, Institute for Medical Research - Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
  • Assouline B; Department of Developmental Biology and Cancer Research, Institute for Medical Research - Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
  • Winter E; Info-CORE, Bioinformatics Unit of the I-CORE Computation Center at the Hebrew University and Hadassah, Jerusalem, Israel.
  • Ruppo S; Info-CORE, Bioinformatics Unit of the I-CORE Computation Center at the Hebrew University and Hadassah, Jerusalem, Israel.
  • Nevo Y; Info-CORE, Bioinformatics Unit of the I-CORE Computation Center at the Hebrew University and Hadassah, Jerusalem, Israel.
  • Maly A; Department of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
  • Meir K; Department of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
  • Witkiewicz AK; Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, USA.
  • Cohen J; Department of Cell and Developmental Biology, Sackler Faculty of Medicine Tel Aviv University, Tel Aviv, Israel.
  • Rizou SV; Department of Histology and Embryology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
  • Pikarsky E; Department of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
  • Luxenburg C; The Lautenberg Center for Immunology and Cancer Research, Hebrew University of Jerusalem Faculty of Medicine, Jerusalem, Israel.
  • Gorgoulis VG; Department of Cell and Developmental Biology, Sackler Faculty of Medicine Tel Aviv University, Tel Aviv, Israel.
  • Ben-Porath I; Department of Histology and Embryology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Nat Commun ; 11(1): 2711, 2020 06 01.
Article em En | MEDLINE | ID: mdl-32483135

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transformação Celular Neoplásica / Inibidor p16 de Quinase Dependente de Ciclina / Epiderme / Via de Sinalização Wnt Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transformação Celular Neoplásica / Inibidor p16 de Quinase Dependente de Ciclina / Epiderme / Via de Sinalização Wnt Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article