Human laminin-111 and laminin-211 protein therapy prevents muscle disease progression in an immunodeficient mouse model of LAMA2-CMD.

Barraza-Flores, Pamela; Hermann, Hailey J; Bates, Christina R; Allen, Tyler G; Grunert, Timothy T; Burkin, Dean J

Barraza-Flores, Pamela; Hermann, Hailey J; Bates, Christina R; Allen, Tyler G; Grunert, Timothy T; Burkin, Dean J.

Afiliação

Barraza-Flores P; Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno, NV, 89557, USA.
Hermann HJ; Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno, NV, 89557, USA.
Bates CR; Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno, NV, 89557, USA.
Allen TG; Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno, NV, 89557, USA.
Grunert TT; Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno, NV, 89557, USA.
Burkin DJ; Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno, NV, 89557, USA. dburkin@med.unr.edu.

Skelet Muscle ; 10(1): 18, 2020 06 04.

Article em En | MEDLINE | ID: mdl-32498713

Assuntos

Terapia Genética/métodos; Laminina/genética; Distrofias Musculares/terapia; Animais; Humanos; Laminina/metabolismo; Camundongos; Camundongos Endogâmicos NOD; Camundongos SCID; Músculo Esquelético/metabolismo; Distrofias Musculares/genética; Distrofias Musculares/imunologia; Proteínas Recombinantes/genética; Proteínas Recombinantes/metabolismo

Palavras-chave

Immune system; LAMA2-CMD; Laminin-111; MDC1A

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Genética / Laminina / Distrofias Musculares Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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