Nutrient-dependent control of RNA polymerase II elongation rate regulates specific gene expression programs by alternative polyadenylation.

Yague-Sanz, Carlo; Vanrobaeys, Yann; Fernandez, Ronan; Duval, Maxime; Larochelle, Marc; Beaudoin, Jude; Berro, Julien; Labbé, Simon; Jacques, Pierre-Étienne; Bachand, François

Yague-Sanz, Carlo; Vanrobaeys, Yann; Fernandez, Ronan; Duval, Maxime; Larochelle, Marc; Beaudoin, Jude; Berro, Julien; Labbé, Simon; Jacques, Pierre-Étienne; Bachand, François.

Afiliação

Yague-Sanz C; Department of Biochemistry and Functional Genomics, Université de Sherbrooke, Sherbrooke, Québec J1E 4K8, Canada.
Vanrobaeys Y; Department of Biochemistry and Functional Genomics, Université de Sherbrooke, Sherbrooke, Québec J1E 4K8, Canada.
Fernandez R; Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, Connecticut 06520, USA.
Duval M; Department of Cell Biology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
Larochelle M; Department of Biochemistry and Functional Genomics, Université de Sherbrooke, Sherbrooke, Québec J1E 4K8, Canada.
Beaudoin J; Department of Biochemistry and Functional Genomics, Université de Sherbrooke, Sherbrooke, Québec J1E 4K8, Canada.
Berro J; Department of Biochemistry and Functional Genomics, Université de Sherbrooke, Sherbrooke, Québec J1E 4K8, Canada.
Labbé S; Department of Molecular Biophysics and Biochemistry, Yale School of Medicine, New Haven, Connecticut 06520, USA.
Jacques PÉ; Department of Cell Biology, Yale School of Medicine, New Haven, Connecticut 06520, USA.
Bachand F; Department of Biochemistry and Functional Genomics, Université de Sherbrooke, Sherbrooke, Québec J1E 4K8, Canada.

Genes Dev ; 34(13-14): 883-897, 2020 07 01.

Article em En | MEDLINE | ID: mdl-32499400

Assuntos

Regulação da Expressão Gênica/efeitos dos fármacos; RNA Polimerase II/genética; Schizosaccharomyces/enzimologia; Schizosaccharomyces/genética; Ativação Enzimática/efeitos dos fármacos; Genes Fúngicos/genética; Mutação; Elongação Traducional da Cadeia Peptídica/efeitos dos fármacos; Fosfatos/farmacologia; Poliadenilação; Regiões Promotoras Genéticas/genética; RNA Polimerase II/química; RNA Polimerase II/metabolismo; Saccharomyces cerevisiae/enzimologia; Saccharomyces cerevisiae/genética; Fatores de Transcrição/genética

Palavras-chave

NTP sensing; RNA polymerase II; alternative polyadenylation; phosphate starvation; transcription elongation rate; transcription termination

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Schizosaccharomyces / RNA Polimerase II / Regulação da Expressão Gênica Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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