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The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype.
Vandamme, Niels; Denecker, Geertrui; Bruneel, Kenneth; Blancke, Gillian; Akay, Özden; Taminau, Joachim; De Coninck, Jordy; De Smedt, Eva; Skrypek, Nicolas; Van Loocke, Wouter; Wouters, Jasper; Nittner, David; Köhler, Corinna; Darling, Douglas S; Cheng, Phil F; Raaijmakers, Marieke I G; Levesque, Mitchell P; Mallya, Udupi Girish; Rafferty, Mairin; Balint, Balazs; Gallagher, William M; Brochez, Lieve; Huylebroeck, Danny; Haigh, Jody J; Andries, Vanessa; Rambow, Florian; Van Vlierberghe, Pieter; Goossens, Steven; van den Oord, Joost J; Marine, Jean-Christophe; Berx, Geert.
Afiliação
  • Vandamme N; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Denecker G; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Bruneel K; VIB-UGent Center for Inflammation Research, Ghent, Belgium.
  • Blancke G; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Akay Ö; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Taminau J; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • De Coninck J; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • De Smedt E; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Skrypek N; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Van Loocke W; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Wouters J; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Nittner D; VIB-UGent Center for Inflammation Research, Ghent, Belgium.
  • Köhler C; Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, Leuven, Belgium.
  • Darling DS; Laboratory for Molecular Cancer Biology, Department of Oncology, KULeuven, Leuven, Belgium.
  • Cheng PF; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Raaijmakers MIG; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Levesque MP; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Mallya UG; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Rafferty M; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Balint B; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Gallagher WM; Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  • Brochez L; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Huylebroeck D; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
  • Haigh JJ; Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University and University Hospital, Ghent, Belgium.
  • Andries V; Laboratory of Translational Cell and Tissue Research, Department of Pathology, KULeuven and UZ Leuven, Leuven, Belgium.
  • Rambow F; Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, Leuven, Belgium.
  • Van Vlierberghe P; Laboratory for Molecular Cancer Biology, Department of Oncology, KULeuven, Leuven, Belgium.
  • Goossens S; Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, Leuven, Belgium.
  • van den Oord JJ; Laboratory for Molecular Cancer Biology, Department of Oncology, KULeuven, Leuven, Belgium.
  • Marine JC; Department of Oral Immunology and Infectious Diseases, and Center for Genetics and Molecular Medicine, University of Louisville, Louisville, Kentucky.
  • Berx G; Department of Dermatology, University of Zurich, University of Zurich Hospital, Zurich, Switzerland.
Cancer Res ; 80(14): 2983-2995, 2020 07 15.
Article em En | MEDLINE | ID: mdl-32503808
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Regulação Neoplásica da Expressão Gênica / Proliferação de Células / Transição Epitelial-Mesenquimal / Homeobox 2 de Ligação a E-box com Dedos de Zinco / Neoplasias Pulmonares / Melanoma Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Regulação Neoplásica da Expressão Gênica / Proliferação de Células / Transição Epitelial-Mesenquimal / Homeobox 2 de Ligação a E-box com Dedos de Zinco / Neoplasias Pulmonares / Melanoma Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article