miR-20b-5p attenuates hypoxia-induced apoptosis in cardiomyocytes via the HIF-1&#945;/NF-&#954;B pathway.

Zhou, Zhongquan; Chen, Songwen; Tian, Zhiming; Deng, Shibing; Yi, Xuying; Yang, Shaning; Yang, Xuexin; Jin, Lijun; Shi, Wanqing

miR-20b-5p attenuates hypoxia-induced apoptosis in cardiomyocytes via the HIF-1α/NF-κB pathway.

Zhou, Zhongquan; Chen, Songwen; Tian, Zhiming; Deng, Shibing; Yi, Xuying; Yang, Shaning; Yang, Xuexin; Jin, Lijun; Shi, Wanqing.

Afiliação

Zhou Z; Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China.
Chen S; Department of Cardiology, Shanghai General Hospital, Shanghai 200000, China.
Tian Z; Department of Cardiology, First School of Clinical Medicine College, Yangtze University, Jingzhou 434000, China.
Deng S; Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China.
Yi X; Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China.
Yang S; Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China.
Yang X; Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China.
Jin L; Department of Cardiology, The First Hospital of Jingzhou City (the First Affiliated Hospital of Yangtze University), Jingzhou 434000, China.
Shi W; The First Hospital of Jingzhou City, The Interventional Center, Jingzhou 434000, China.

Acta Biochim Biophys Sin (Shanghai) ; 52(9): 927-934, 2020 Sep 08.

Article em En | MEDLINE | ID: mdl-32510153

Assuntos

Apoptose; Regulação da Expressão Gênica; Subunidade alfa do Fator 1 Induzível por Hipóxia/biossíntese; Miócitos Cardíacos/metabolismo; NF-kappa B/metabolismo; Transdução de Sinais; Idoso; Animais; Hipóxia Celular; Linhagem Celular; Feminino; Humanos; Subunidade alfa do Fator 1 Induzível por Hipóxia/genética; Masculino; Pessoa de Meia-Idade; Miócitos Cardíacos/patologia; NF-kappa B/genética; Ratos

Palavras-chave

NF-κB; cardiomyocytes; hypoxia; hypoxia-inducible factor-1; miR-20b-5p

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Regulação da Expressão Gênica / NF-kappa B / Apoptose / Miócitos Cardíacos / Subunidade alfa do Fator 1 Induzível por Hipóxia Tipo de estudo: Prognostic_studies Limite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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