RNA N-6-methyladenosine enzymes and resistance of cancer cells to chemotherapy and radiotherapy.

Xiang, Meiyi; Liu, Wensu; Tian, Wei; You, Abin; Deng, Dajun

Xiang, Meiyi; Liu, Wensu; Tian, Wei; You, Abin; Deng, Dajun.

Afiliação

Xiang M; Key Laboratory of Carcinogenesis & Translational Research (Ministry of Education/Beijing), Division of Etiology, Peking University Cancer Hospital & Institute, Fu-Cheng-Lu #52, Haidian District, Beijing 100142, PR China.
Liu W; Key Laboratory of Carcinogenesis & Translational Research (Ministry of Education/Beijing), Division of Etiology, Peking University Cancer Hospital & Institute, Fu-Cheng-Lu #52, Haidian District, Beijing 100142, PR China.
Tian W; Key Laboratory of Carcinogenesis & Translational Research (Ministry of Education/Beijing), Division of Etiology, Peking University Cancer Hospital & Institute, Fu-Cheng-Lu #52, Haidian District, Beijing 100142, PR China.
You A; Key Laboratory of Carcinogenesis & Translational Research (Ministry of Education/Beijing), Division of Etiology, Peking University Cancer Hospital & Institute, Fu-Cheng-Lu #52, Haidian District, Beijing 100142, PR China.
Deng D; Key Laboratory of Carcinogenesis & Translational Research (Ministry of Education/Beijing), Division of Etiology, Peking University Cancer Hospital & Institute, Fu-Cheng-Lu #52, Haidian District, Beijing 100142, PR China.

Epigenomics ; 12(9): 801-809, 2020 05.

Article em En | MEDLINE | ID: mdl-32515221

Assuntos

Adenosina/análogos & derivados; Resistencia a Medicamentos Antineoplásicos; Neoplasias/enzimologia; Adenosina/metabolismo; Homólogo AlkB 5 da RNA Desmetilase; Dioxigenase FTO Dependente de alfa-Cetoglutarato/metabolismo; Proteínas de Ciclo Celular/metabolismo; Resistencia a Medicamentos Antineoplásicos/genética; Humanos; Metilação; Metiltransferases/metabolismo; Neoplasias/tratamento farmacológico; Neoplasias/genética; Neoplasias/radioterapia; RNA/química; RNA/metabolismo; Fatores de Processamento de RNA/metabolismo; Tolerância a Radiação

Palavras-chave

ALKBH5; FTO; METTL14; METTL3; RNA methylation; WTAP; cancer; drug resistance; m6A

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adenosina / Resistencia a Medicamentos Antineoplásicos / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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