CKD Increases Carbonylation of HDL and Is Associated with Impaired Antiaggregant Properties.

Florens, Nans; Calzada, Catherine; Lemoine, Sandrine; Boulet, Marie Michèle; Guillot, Nicolas; Barba, Christophe; Roux, Julie; Delolme, Fréderic; Page, Adeline; Poux, Jean Michel; Laville, Maurice; Moulin, Philippe; Soulère, Laurent; Guebre-Egziabher, Fitsum; Juillard, Laurent; Soulage, Christophe O

Florens, Nans; Calzada, Catherine; Lemoine, Sandrine; Boulet, Marie Michèle; Guillot, Nicolas; Barba, Christophe; Roux, Julie; Delolme, Fréderic; Page, Adeline; Poux, Jean Michel; Laville, Maurice; Moulin, Philippe; Soulère, Laurent; Guebre-Egziabher, Fitsum; Juillard, Laurent; Soulage, Christophe O.

Afiliação

Florens N; CarMeN Laboratory, University of Lyon, Institut National de la Santé et de la Recherche Médicale (INSERM) U1060, Institut National des Sciences Appliquées de Lyon (INSA-Lyon), Claude Bernard University Lyon 1, Institut National de la Recherche Agronomique (INRA) U1397, Villeurbanne, France nans.flor
Calzada C; Department of Nephrology, University Hospital of Lyon, E. Herriot Hospital, Lyon, France.
Lemoine S; CarMeN Laboratory, University of Lyon, Institut National de la Santé et de la Recherche Médicale (INSERM) U1060, Institut National des Sciences Appliquées de Lyon (INSA-Lyon), Claude Bernard University Lyon 1, Institut National de la Recherche Agronomique (INRA) U1397, Villeurbanne, France.
Boulet MM; CarMeN Laboratory, University of Lyon, Institut National de la Santé et de la Recherche Médicale (INSERM) U1060, Institut National des Sciences Appliquées de Lyon (INSA-Lyon), Claude Bernard University Lyon 1, Institut National de la Recherche Agronomique (INRA) U1397, Villeurbanne, France.
Guillot N; Department of Nephrology, University Hospital of Lyon, E. Herriot Hospital, Lyon, France.
Barba C; CarMeN Laboratory, University of Lyon, Institut National de la Santé et de la Recherche Médicale (INSERM) U1060, Institut National des Sciences Appliquées de Lyon (INSA-Lyon), Claude Bernard University Lyon 1, Institut National de la Recherche Agronomique (INRA) U1397, Villeurbanne, France.
Roux J; CarMeN Laboratory, University of Lyon, Institut National de la Santé et de la Recherche Médicale (INSERM) U1060, Institut National des Sciences Appliquées de Lyon (INSA-Lyon), Claude Bernard University Lyon 1, Institut National de la Recherche Agronomique (INRA) U1397, Villeurbanne, France.
Delolme F; CarMeN Laboratory, University of Lyon, Institut National de la Santé et de la Recherche Médicale (INSERM) U1060, Institut National des Sciences Appliquées de Lyon (INSA-Lyon), Claude Bernard University Lyon 1, Institut National de la Recherche Agronomique (INRA) U1397, Villeurbanne, France.
Page A; CarMeN Laboratory, University of Lyon, Institut National de la Santé et de la Recherche Médicale (INSERM) U1060, Institut National des Sciences Appliquées de Lyon (INSA-Lyon), Claude Bernard University Lyon 1, Institut National de la Recherche Agronomique (INRA) U1397, Villeurbanne, France.
Poux JM; Protein Science Facility, SFR BioSciences, Centre National de la Recherche Scientifique (CNRS) UMS3444, INSERM US8, Claude Bernard University Lyon 1, École Normale Supérieure de Lyon (ENS de Lyon), Lyon, France.
Laville M; Protein Science Facility, SFR BioSciences, Centre National de la Recherche Scientifique (CNRS) UMS3444, INSERM US8, Claude Bernard University Lyon 1, École Normale Supérieure de Lyon (ENS de Lyon), Lyon, France.
Moulin P; Association Pour l'Utilisation du Rein Artificiel dans la Région Lyonnaise (AURAL), Lyon, France.
Soulère L; Association Pour l'Utilisation du Rein Artificiel dans la Région Lyonnaise (AURAL), Lyon, France.
Guebre-Egziabher F; CarMeN Laboratory, University of Lyon, Institut National de la Santé et de la Recherche Médicale (INSERM) U1060, Institut National des Sciences Appliquées de Lyon (INSA-Lyon), Claude Bernard University Lyon 1, Institut National de la Recherche Agronomique (INRA) U1397, Villeurbanne, France.
Juillard L; Department of Endocrinology, University Hospital of Lyon, L. Pradel Hospital, Bron, France.
Soulage CO; Institute for Molecular and Supramolecular Chemistry and Biochemistry, University of Lyon, INSA-Lyon, UMR 5246 CNRS, Villeurbanne, France.

J Am Soc Nephrol ; 31(7): 1462-1477, 2020 07.

Article em En | MEDLINE | ID: mdl-32518085

Assuntos

Aldeídos/sangue; Lipoproteínas HDL/sangue; Lipoproteínas HDL/farmacologia; Estresse Oxidativo; Agregação Plaquetária/efeitos dos fármacos; Insuficiência Renal Crônica/sangue; Adulto; Idoso; Idoso de 80 Anos ou mais; Animais; Anticorpos/farmacologia; Plaquetas; Antígenos CD36/imunologia; Células Cultivadas; Modelos Animais de Doenças; Feminino; Humanos; Proteínas Quinases JNK Ativadas por Mitógeno/metabolismo; Masculino; Malondialdeído/sangue; Pessoa de Meia-Idade; Oxirredução; Diálise Peritoneal; Fosforilação; Carbonilação Proteica; Inibidores de Proteínas Quinases/farmacologia; Coelhos; Insuficiência Renal Crônica/terapia; Quinases da Família src/antagonistas & inibidores; Quinases da Família src/metabolismo

Palavras-chave

cardiovascular disease; chronic kidney disease; dialysis; dyslipidemia; platelets; thrombosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Agregação Plaquetária / Estresse Oxidativo / Aldeídos / Insuficiência Renal Crônica / Lipoproteínas HDL Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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