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Understanding the Effect of Hydroxypropyl-ß-Cyclodextrin on Fenebrutinib Absorption in an Itraconazole-Fenebrutinib Drug-Drug Interaction Study.
Durk, Matthew R; Jones, Nicholas S; Liu, Jia; Nagapudi, Karthik; Mao, Chen; Plise, Emile G; Wong, Susan; Chen, Jacob Z; Chen, Yuan; Chinn, Leslie W; Chiang, Po-Chang.
Afiliação
  • Durk MR; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Jones NS; Department of Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
  • Liu J; Department of Small Molecule Pharmaceutical Sciences, Genentech, Inc., South San Francisco, California, USA.
  • Nagapudi K; Department of Small Molecule Pharmaceutical Sciences, Genentech, Inc., South San Francisco, California, USA.
  • Mao C; Department of Small Molecule Pharmaceutical Sciences, Genentech, Inc., South San Francisco, California, USA.
  • Plise EG; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Wong S; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Chen JZ; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Chen Y; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA.
  • Chinn LW; Department of Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.
  • Chiang PC; Department of Small Molecule Pharmaceutical Sciences, Genentech, Inc., South San Francisco, California, USA.
Clin Pharmacol Ther ; 108(6): 1224-1232, 2020 12.
Article em En | MEDLINE | ID: mdl-32535897
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Piridonas / Itraconazol / Inibidores de Proteínas Quinases / Excipientes / 2-Hidroxipropil-beta-Ciclodextrina / Absorção Intestinal Limite: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperazinas / Piridonas / Itraconazol / Inibidores de Proteínas Quinases / Excipientes / 2-Hidroxipropil-beta-Ciclodextrina / Absorção Intestinal Limite: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article