Your browser doesn't support javascript.
loading
Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury.
Monroe, James J; Tanis, Keith Q; Podtelezhnikov, Alexei A; Nguyen, Truyen; Machotka, Sam V; Lynch, Donna; Evers, Raymond; Palamanda, Jairam; Miller, Randy R; Pippert, Todd; Cabalu, Tamara D; Johnson, Timothy E; Aslamkhan, Amy G; Kang, Wen; Tamburino, Alex M; Mitra, Kaushik; Agrawal, Nancy G B; Sistare, Frank D.
Afiliação
  • Monroe JJ; Safety Assessment & Laboratory Animal Resources.
  • Tanis KQ; Human Genetics & Pharmacogenomics.
  • Podtelezhnikov AA; Human Genetics & Pharmacogenomics.
  • Nguyen T; Safety Assessment & Laboratory Animal Resources.
  • Machotka SV; Safety Assessment & Laboratory Animal Resources.
  • Lynch D; Safety Assessment & Laboratory Animal Resources.
  • Evers R; Pharmacokinetics, Pharmacodynamics & Drug Metabolism, Merck & Co., Inc, West Point, Pennsylvania 19486.
  • Palamanda J; Pharmacokinetics, Pharmacodynamics & Drug Metabolism, Merck & Co., Inc, West Point, Pennsylvania 19486.
  • Miller RR; Pharmacokinetics, Pharmacodynamics & Drug Metabolism, Merck & Co., Inc, West Point, Pennsylvania 19486.
  • Pippert T; Safety Assessment & Laboratory Animal Resources.
  • Cabalu TD; Pharmacokinetics, Pharmacodynamics & Drug Metabolism, Merck & Co., Inc, West Point, Pennsylvania 19486.
  • Johnson TE; Safety Assessment & Laboratory Animal Resources.
  • Aslamkhan AG; Safety Assessment & Laboratory Animal Resources.
  • Kang W; Safety Assessment & Laboratory Animal Resources.
  • Tamburino AM; Human Genetics & Pharmacogenomics.
  • Mitra K; Safety Assessment & Laboratory Animal Resources.
  • Agrawal NGB; Janssen Research & Development, LLC, Spring House, PA 19486.
  • Sistare FD; Pharmacokinetics, Pharmacodynamics & Drug Metabolism, Merck & Co., Inc, West Point, Pennsylvania 19486.
Toxicol Sci ; 177(1): 281-299, 2020 09 01.
Article em En | MEDLINE | ID: mdl-32559301
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Doença Hepática Induzida por Substâncias e Drogas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Doença Hepática Induzida por Substâncias e Drogas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article