Place Your BETs in Combination Therapy.

Liddicoat, Brian J; Dawson, Mark A

Liddicoat, Brian J; Dawson, Mark A.

Afiliação

Liddicoat BJ; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, VIC 3052, Australia.
Dawson MA; Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, VIC 3052, Australia; Centre for Cancer Research, University of Melbourne, Melbourne, Australia. Electronic address: mark.dawson@petermac.org.

Mol Cell ; 78(6): 991-993, 2020 06 18.

Article em En | MEDLINE | ID: mdl-32559426

ABSTRACT

ABSTRACT

Combination therapy remains the cornerstone for cancer management, and understanding how to rationally partner drugs is imperative. In this issue of Molecular Cell, Shu et al. (2020) provide a tour de force multi-omic approach to identify synergistic pathways that increase the efficacy of BET bromodomain inhibitors in triple-negative breast cancer.

Assuntos

Antineoplásicos; Neoplasias de Mama Triplo Negativas; Humanos; Proteínas Nucleares

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias de Mama Triplo Negativas / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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