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Machine learning guided association of adverse drug reactions with in vitro target-based pharmacology.
Ietswaart, Robert; Arat, Seda; Chen, Amanda X; Farahmand, Saman; Kim, Bumjun; DuMouchel, William; Armstrong, Duncan; Fekete, Alexander; Sutherland, Jeffrey J; Urban, Laszlo.
Afiliação
  • Ietswaart R; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, United States. Electronic address: robert_ietswaart@hms.harvard.edu.
  • Arat S; The Jackson Laboratory, Farmington, CT 06032, United States. Electronic address: seda8arat@gmail.com.
  • Chen AX; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, United States; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, United States.
  • Farahmand S; Computational Sciences PhD program, University of Massachusetts Boston, Boston, MA 02125, United States.
  • Kim B; Department of Chemical Engineering, Northeastern University, Boston, MA 02115, United States.
  • DuMouchel W; Oracle Health Sciences, Burlington, MA 01803, United States.
  • Armstrong D; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, United States.
  • Fekete A; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, United States.
  • Sutherland JJ; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, United States. Electronic address: jeffrey.sutherland@novartis.com.
  • Urban L; Novartis Institutes for Biomedical Research, Cambridge, MA 02139, United States. Electronic address: laszlo.urban@novartis.com.
EBioMedicine ; 57: 102837, 2020 Jul.
Article em En | MEDLINE | ID: mdl-32565027
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos / Aprendizado de Máquina Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos / Aprendizado de Máquina Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article