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Manumycin polyketides act as molecular glues between UBR7 and P53.
Isobe, Yosuke; Okumura, Mikiko; McGregor, Lynn M; Brittain, Scott M; Jones, Michael D; Liang, Xiaoyou; White, Ross; Forrester, William; McKenna, Jeffrey M; Tallarico, John A; Schirle, Markus; Maimone, Thomas J; Nomura, Daniel K.
Afiliação
  • Isobe Y; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.
  • Okumura M; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, Berkeley, CA, USA.
  • McGregor LM; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.
  • Brittain SM; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, Berkeley, CA, USA.
  • Jones MD; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Liang X; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • White R; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Forrester W; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • McKenna JM; Department of Chemistry, University of California, Berkeley, Berkeley, CA, USA.
  • Tallarico JA; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, Berkeley, CA, USA.
  • Schirle M; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
  • Maimone TJ; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, Berkeley, CA, USA.
  • Nomura DK; Novartis Institutes for BioMedical Research, Cambridge, MA, USA.
Nat Chem Biol ; 16(11): 1189-1198, 2020 11.
Article em En | MEDLINE | ID: mdl-32572277
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polienos / Neoplasias da Mama / Proteína Supressora de Tumor p53 / Ubiquitina-Proteína Ligases / Alcamidas Poli-Insaturadas / Policetídeos / Antineoplásicos Limite: Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polienos / Neoplasias da Mama / Proteína Supressora de Tumor p53 / Ubiquitina-Proteína Ligases / Alcamidas Poli-Insaturadas / Policetídeos / Antineoplásicos Limite: Female / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article