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Identification of RT-PCR-Negative Asymptomatic COVID-19 Patients via Serological Testing.
Wu, Jinru; Liu, Xinyi; Zhou, Dan; Qiu, Guangqian; Dai, Miao; Yang, Qingting; Pan, Zhonghui; Zhou, Ning; Wu, Pa.
Afiliação
  • Wu J; College of Life Science, Hunan Normal University, Changsha, China.
  • Liu X; Loudi Center for Disease Control and Prevention, Loudi, China.
  • Zhou D; College of Life Science, Hunan Normal University, Changsha, China.
  • Qiu G; Loudi Center for Disease Control and Prevention, Loudi, China.
  • Dai M; Loudi Center for Disease Control and Prevention, Loudi, China.
  • Yang Q; Loudi Center for Disease Control and Prevention, Loudi, China.
  • Pan Z; Loudi Center for Disease Control and Prevention, Loudi, China.
  • Zhou N; Xinhua Center for Disease Control and Prevention, Xinhua, China.
  • Wu P; Department of Infectious Diseases, The Second Xiangya Hospital, Central South University, Changsha, China.
Front Public Health ; 8: 267, 2020.
Article em En | MEDLINE | ID: mdl-32582617
Asymptomatic individuals with coronavirus disease (COVID-19) have been identified via nucleic acid testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, the epidemiologic characteristics and viral shedding pattern of asymptomatic patients remain largely unknown. In this study, serological testing was applied when identifying nine asymptomatic cases of COVID-19 who showed persistent negative RT-PCR test results for SARS-CoV-2 nucleic acid and no symptoms of COVID-19. Two asymptomatic cases were presumed to be index patients who had cleared the virus when their close contacts developed symptoms of COVID-19. Three of the asymptomatic cases were local individuals who spontaneously recovered before their presumed index patients developed symptoms of COVID-19. This report presents the epidemiologic and clinical characteristics of asymptomatic individuals with SARS-CoV-2 infection that were undetected on RT-PCR tests in previous epidemiologic investigations probably due to the transient viral shedding duration.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reação em Cadeia da Polimerase Via Transcriptase Reversa / Doenças Assintomáticas / Teste Sorológico para COVID-19 / COVID-19 Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reação em Cadeia da Polimerase Via Transcriptase Reversa / Doenças Assintomáticas / Teste Sorológico para COVID-19 / COVID-19 Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article