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Loss of CLN3, the gene mutated in juvenile neuronal ceroid lipofuscinosis, leads to metabolic impairment and autophagy induction in retinal pigment epithelium.
Zhong, Yu; Mohan, Kabhilan; Liu, Jinpeng; Al-Attar, Ahmad; Lin, Penghui; Flight, Robert M; Sun, Qiushi; Warmoes, Marc O; Deshpande, Rahul R; Liu, Huijuan; Jung, Kyung Sik; Mitov, Mihail I; Lin, Nianwei; Butterfield, D Allan; Lu, Shuyan; Liu, Jinze; Moseley, Hunter N B; Fan, Teresa W M; Kleinman, Mark E; Wang, Qing Jun.
Afiliação
  • Zhong Y; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, United States.
  • Mohan K; Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY, United States.
  • Liu J; Markey Cancer Center, University of Kentucky, Lexington, KY, United States.
  • Al-Attar A; Center for Environmental and Systems Biochemistry, University of Kentucky, Lexington, KY, United States.
  • Lin P; Center for Environmental and Systems Biochemistry, University of Kentucky, Lexington, KY, United States.
  • Flight RM; Markey Cancer Center, University of Kentucky, Lexington, KY, United States; Center for Environmental and Systems Biochemistry, University of Kentucky, Lexington, KY, United States.
  • Sun Q; Center for Environmental and Systems Biochemistry, University of Kentucky, Lexington, KY, United States.
  • Warmoes MO; Center for Environmental and Systems Biochemistry, University of Kentucky, Lexington, KY, United States.
  • Deshpande RR; Center for Environmental and Systems Biochemistry, University of Kentucky, Lexington, KY, United States.
  • Liu H; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, United States.
  • Jung KS; Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY, United States.
  • Mitov MI; Markey Cancer Center, University of Kentucky, Lexington, KY, United States.
  • Lin N; Pfizer Inc., San Diego, CA, United States.
  • Butterfield DA; Markey Cancer Center, University of Kentucky, Lexington, KY, United States; Department of Chemistry, University of Kentucky, Lexington, KY, United States.
  • Lu S; Pfizer Inc., San Diego, CA, United States.
  • Liu J; Markey Cancer Center, University of Kentucky, Lexington, KY, United States; Department of Computer Science, University of Kentucky, Lexington, KY, United States; Institute for Biomedical Informatics, University of Kentucky, Lexington, KY, United States.
  • Moseley HNB; Markey Cancer Center, University of Kentucky, Lexington, KY, United States; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, United States; Institute for Biomedical Informatics, University of Kentucky, Lexington, KY, United States.
  • Fan TWM; Markey Cancer Center, University of Kentucky, Lexington, KY, United States; Center for Environmental and Systems Biochemistry, University of Kentucky, Lexington, KY, United States; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, United States.
  • Kleinman ME; Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY, United States.
  • Wang QJ; Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY, United States; Markey Cancer Center, University of Kentucky, Lexington, KY, United States. Electronic address: qingjun.wang@uky.edu.
Biochim Biophys Acta Mol Basis Dis ; 1866(10): 165883, 2020 10 01.
Article em En | MEDLINE | ID: mdl-32592935
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Cegueira / Epitélio Pigmentado da Retina / Lipofuscinoses Ceroides Neuronais Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas de Membrana / Cegueira / Epitélio Pigmentado da Retina / Lipofuscinoses Ceroides Neuronais Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article