The effects of phenotypic plasticity on the fixation probability of mutant cancer stem cells.

Eastman, Brydon; Wodarz, Dominik; Kohandel, Mohammad

Eastman, Brydon; Wodarz, Dominik; Kohandel, Mohammad.

Afiliação

Eastman B; Department of Applied Mathematics, University of Waterloo, Waterloo N2L 3G1, Canada; Department of Population Health and Disease Prevention Program in Public Health, Susan and Henry Samueli College of Health Sciences, University of California, Irvine, Irvine CA 92697, USA. Electronic address: b2eastma@uwaterloo.ca.
Wodarz D; Department of Applied Mathematics, University of Waterloo, Waterloo N2L 3G1, Canada; Department of Population Health and Disease Prevention Program in Public Health, Susan and Henry Samueli College of Health Sciences, University of California, Irvine, Irvine CA 92697, USA.
Kohandel M; Department of Applied Mathematics, University of Waterloo, Waterloo N2L 3G1, Canada.

J Theor Biol ; 503: 110384, 2020 10 21.

Article em En | MEDLINE | ID: mdl-32603669

Assuntos

Neoplasias; Células-Tronco Neoplásicas; Adaptação Fisiológica; Diferenciação Celular; Humanos; Neoplasias/genética; Probabilidade

Palavras-chave

Cancer stem cells; De-differentiation; Fixation probability; Plasticity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Neoplásicas / Neoplasias Tipo de estudo: Qualitative_research Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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