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Bootstrap inference for multiple imputation under uncongeniality and misspecification.
Bartlett, Jonathan W; Hughes, Rachael A.
Afiliação
  • Bartlett JW; Department of Mathematical Sciences, University of Bath, Bath, UK.
  • Hughes RA; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Stat Methods Med Res ; 29(12): 3533-3546, 2020 12.
Article em En | MEDLINE | ID: mdl-32605503
Multiple imputation has become one of the most popular approaches for handling missing data in statistical analyses. Part of this success is due to Rubin's simple combination rules. These give frequentist valid inferences when the imputation and analysis procedures are so-called congenial and the embedding model is correctly specified, but otherwise may not. Roughly speaking, congeniality corresponds to whether the imputation and analysis models make different assumptions about the data. In practice, imputation models and analysis procedures are often not congenial, such that tests may not have the correct size, and confidence interval coverage deviates from the advertised level. We examine a number of recent proposals which combine bootstrapping with multiple imputation and determine which are valid under uncongeniality and model misspecification. Imputation followed by bootstrapping generally does not result in valid variance estimates under uncongeniality or misspecification, whereas certain bootstrap followed by imputation methods do. We recommend a particular computationally efficient variant of bootstrapping followed by imputation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Modelos Estatísticos Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Modelos Estatísticos Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article