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Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae.
Prada-Luengo, Iñigo; Møller, Henrik D; Henriksen, Rasmus A; Gao, Qian; Larsen, Camilla Eggert; Alizadeh, Sefa; Maretty, Lasse; Houseley, Jonathan; Regenberg, Birgitte.
Afiliação
  • Prada-Luengo I; Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.
  • Møller HD; Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.
  • Henriksen RA; Department of Biology, Institute of Biochemistry, ETH Zürich, Zurich CH-8093, Switzerland.
  • Gao Q; Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.
  • Larsen CE; Epigenetics Programme, The Babraham Institute, Babraham, Cambridge CB22 3-AT, UK.
  • Alizadeh S; Adaptimmune Ltd, Oxfordshire OX14 4RX, UK.
  • Maretty L; Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.
  • Houseley J; Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.
  • Regenberg B; Department of Molecular Medicine, Aarhus University Hospital, Aarhus DK-8200, Denmark.
Nucleic Acids Res ; 48(14): 7883-7898, 2020 08 20.
Article em En | MEDLINE | ID: mdl-32609810
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / DNA Circular / Senescência Celular / Replicação do DNA Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / DNA Circular / Senescência Celular / Replicação do DNA Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article