Nrf2/HO-1 partially regulates cytoprotective effects of carbon monoxide against urban particulate matter-induced inflammatory responses in oral keratinocytes.

Cheng, Ching-Yi; Vo, Thi Thuy Tien; Lin, Wei-Ning; Huang, Hsiang-Wei; Chuang, Chu-Chun; Chu, Pei-Ming; Lee, I-Ta

Cheng, Ching-Yi; Vo, Thi Thuy Tien; Lin, Wei-Ning; Huang, Hsiang-Wei; Chuang, Chu-Chun; Chu, Pei-Ming; Lee, I-Ta.

Afiliação

Cheng CY; Graduate Institute of Health Industry Technology, Research Center for Chinese Herbal Medicine and Research Center for Food and Cosmetic Safety, Chang Gung University of Science and Technology, Taoyuan, Taiwan; Department of Pulmonary Infection and Immunology, Chang Gung Memorial Hospital at Linkou,
Vo TTT; School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Lin WN; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City 242, Taiwan.
Huang HW; School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Chuang CC; International MS/PhD Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Chu PM; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.
Lee IT; School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address: itlee0128@tmu.edu.tw.

Cytokine ; 133: 155185, 2020 09.

Article em En | MEDLINE | ID: mdl-32615411

Assuntos

Monóxido de Carbono/farmacologia; Heme Oxigenase-1/metabolismo; Inflamassomos/efeitos dos fármacos; Queratinócitos/efeitos dos fármacos; Fator 2 Relacionado a NF-E2/metabolismo; Material Particulado/farmacologia; Substâncias Protetoras/farmacologia; Anti-Inflamatórios/farmacologia; Células Cultivadas; Humanos; Inflamassomos/metabolismo; Inflamação/induzido quimicamente; Inflamação/metabolismo; Queratinócitos/metabolismo; Mitocôndrias/efeitos dos fármacos; Mitocôndrias/metabolismo; NADPH Oxidases/metabolismo; Compostos Organometálicos/farmacologia; Espécies Reativas de Oxigênio/metabolismo; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

Carbon monoxide; NLRP3 inflammasome; Oral mucosal; Particulate matter; Reactive oxygen species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Monóxido de Carbono / Queratinócitos / Substâncias Protetoras / Heme Oxigenase-1 / Fator 2 Relacionado a NF-E2 / Material Particulado / Inflamassomos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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