Polymerization-Induced Self-Assembly to Produce Prodrug Nanoparticles with Reduction-Responsive Camptothecin Release and pH-Responsive Charge-Reversible Property.

Zhao, Xiao; Chen, Miao; Zhang, Wei-Guo; Wang, Chang-Hui; Wang, Fei; You, Ye-Zi; Zhang, Wen-Jian; Hong, Chun-Yan

Zhao, Xiao; Chen, Miao; Zhang, Wei-Guo; Wang, Chang-Hui; Wang, Fei; You, Ye-Zi; Zhang, Wen-Jian; Hong, Chun-Yan.

Afiliação

Zhao X; CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China.
Chen M; Xi'an Modern Chemistry Research Institute, Xi'an, Shanxi, 710065, China.
Zhang WG; The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, 453100, China.
Wang CH; Department of Cardiology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230026, China.
Wang F; Neurosurgical Department, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230036, China.
You YZ; CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China.
Zhang WJ; CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China.
Hong CY; CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China.

Macromol Rapid Commun ; 41(15): e2000260, 2020 Aug.

Article em En | MEDLINE | ID: mdl-32648310

Assuntos

Portadores de Fármacos/química; Nanopartículas/química; Pró-Fármacos/química; Sobrevivência Celular/efeitos dos fármacos; Liberação Controlada de Fármacos; Etanol/química; Células HeLa; Humanos; Concentração de Íons de Hidrogênio; Interações Hidrofóbicas e Hidrofílicas; Metacrilatos/química; Microscopia Eletrônica de Transmissão; Nanopartículas/ultraestrutura; Nylons/química; Polimerização; Polímeros/química; Ácidos Polimetacrílicos/química; Água/química

Palavras-chave

charge reversal; pH-responsive nanoparticles; polymerization-induced self-assembly; prodrug nanoparticles; reduction-responsive nanoparticles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Portadores de Fármacos / Pró-Fármacos / Nanopartículas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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