Comprehensive clinicopathological and molecular analysis of primary malignant melanoma of the oesophagus.

Tsuyama, Sho; Kohsaka, Shinji; Hayashi, Takuo; Suehara, Yoshiyuki; Hashimoto, Takashi; Kajiyama, Yoshiaki; Tsurumaru, Masahiko; Ueno, Toshihide; Mano, Hiroyuki; Yao, Takashi; Saito, Tsuyoshi

Tsuyama, Sho; Kohsaka, Shinji; Hayashi, Takuo; Suehara, Yoshiyuki; Hashimoto, Takashi; Kajiyama, Yoshiaki; Tsurumaru, Masahiko; Ueno, Toshihide; Mano, Hiroyuki; Yao, Takashi; Saito, Tsuyoshi.

Afiliação

Tsuyama S; Department of Human Pathology, Juntendo University, Graduate School of Medicine, Tokyo, 113-8421, Japan.
Kohsaka S; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, 104-0045, Japan.
Hayashi T; Department of Human Pathology, Juntendo University, Graduate School of Medicine, Tokyo, 113-8421, Japan.
Suehara Y; Intractable Disease Research Center, Juntendo University, Graduate School of Medicine, Tokyo, 113-8421, Japan.
Hashimoto T; Department of Orthopaedic Surgery, Juntendo University School of Medicine, Tokyo, 113-8421, Japan.
Kajiyama Y; Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, Tokyo, 113-8421, Japan.
Tsurumaru M; Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, Tokyo, 113-8421, Japan.
Ueno T; Department of Esophageal and Gastroenterological Surgery, Juntendo University School of Medicine, Tokyo, 113-8421, Japan.
Mano H; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, 104-0045, Japan.
Yao T; Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, 104-0045, Japan.
Saito T; Department of Human Pathology, Juntendo University, Graduate School of Medicine, Tokyo, 113-8421, Japan.

Histopathology ; 78(2): 240-251, 2021 Jan.

Article em En | MEDLINE | ID: mdl-32654197

Assuntos

Neoplasias Esofágicas; Melanoma; Oncogenes/genética; Neoplasias Cutâneas; Idoso; Biomarcadores Tumorais; Neoplasias Esofágicas/genética; Neoplasias Esofágicas/patologia; Esôfago/patologia; Feminino; Sequenciamento de Nucleotídeos em Larga Escala; Humanos; Imuno-Histoquímica; Masculino; Melanoma/genética; Melanoma/patologia; Pessoa de Meia-Idade; Mutação; Neurofibromina 1/genética; Prognóstico; Neoplasias Cutâneas/genética; Neoplasias Cutâneas/patologia; Melanoma Maligno Cutâneo

Palavras-chave

immunotherapy; molecular pathogenesis; next-generation sequencing (NGS); primary malignant melanoma of the oesophagus (PMME); tumour mutation burden (TMB)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oncogenes / Neoplasias Cutâneas / Neoplasias Esofágicas / Melanoma Tipo de estudo: Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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