Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of <i>Trypanosoma cruzi</i> Infection in Heart Endothelial Cells.

Arun, Ashutosh; Rayford, Kayla J; Cooley, Ayorinde; Rachakonda, Girish; Villalta, Fernando; Pratap, Siddharth; Lima, Maria F; Sheibani, Nader; Nde, Pius N

Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Trypanosoma cruzi Infection in Heart Endothelial Cells.

Arun, Ashutosh; Rayford, Kayla J; Cooley, Ayorinde; Rachakonda, Girish; Villalta, Fernando; Pratap, Siddharth; Lima, Maria F; Sheibani, Nader; Nde, Pius N.

Afiliação

Arun A; Department of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Rayford KJ; Department of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Cooley A; Department of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Rachakonda G; Department of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Villalta F; Department of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, TN 37208, USA.
Pratap S; School of Graduate Studies and Research, Meharry Medical College, Nashville, TN 37208, USA.
Lima MF; School of Graduate Studies and Research, Meharry Medical College, Nashville, TN 37208, USA.
Sheibani N; Department of Molecular Cellular and Biomedical Sciences, School of Medicine, The City College of New York, New York, NY 10031, USA.
Nde PN; Department of Ophthalmology and Visual Sciences, Biomedical Engineering and Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.

Int J Mol Sci ; 21(14)2020 Jul 12.

Article em En | MEDLINE | ID: mdl-32664627

Assuntos

Transporte Ativo do Núcleo Celular/fisiologia; Células Endoteliais/parasitologia; Mioblastos/parasitologia; Miocárdio/citologia; Proteínas de Protozoários/fisiologia; Trombospondina 1/fisiologia; Trypanosoma cruzi/fisiologia; Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Animais; Proteínas de Ciclo Celular/metabolismo; Proteínas de Ligação a DNA/metabolismo; Células Endoteliais/metabolismo; Técnicas de Inativação de Genes; Camundongos; Mioblastos/metabolismo; Proteínas Serina-Treonina Quinases/metabolismo; Ratos; Transdução de Sinais/fisiologia; Trombospondina 1/deficiência; Transativadores/fisiologia

Palavras-chave

Chagas heart disease; Trypanosoma cruzi; heart endothelial cells; hippo signaling; transcriptional enhancer factor (TEF) family/TEA domain (TEAD) family; yes-associated protein1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trypanosoma cruzi / Proteínas de Protozoários / Trombospondina 1 / Transporte Ativo do Núcleo Celular / Mioblastos / Células Endoteliais / Miocárdio Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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