Long-term Outcome of Short-course High-dose Glucocorticoids for Severe Acute Respiratory Syndrome (SARS): A 17-Year Follow-up in SARS Survivors.

Sing, Chor-Wing; Tan, Kathryn C B; Wong, Ian C K; Cheung, Bernard M Y; Cheung, Ching-Lung

Sing, Chor-Wing; Tan, Kathryn C B; Wong, Ian C K; Cheung, Bernard M Y; Cheung, Ching-Lung.

Afiliação

Sing CW; Department of Pharmacology and Pharmacy, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, China.
Tan KCB; Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, China.
Wong ICK; Department of Pharmacology and Pharmacy, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, China.
Cheung BMY; Research Department of Practice and Policy, UCL School of Pharmacy, University College London, London, United Kingdom.
Cheung CL; Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, China.

Clin Infect Dis ; 72(10): 1830-1833, 2021 05 18.

Article em En | MEDLINE | ID: mdl-32671407

ABSTRACT

ABSTRACT

Use of high-dose glucocorticoids for COVID-19 (caused by SARS-CoV-2) is controversial because of safety concerns. We examined the long-term consequences of glucocorticoid use in severe acute respiratory syndrome (caused by SARS-CoV-1) survivors. Results showed that high-dose glucocorticoids greatly increased the long-term risk of avascular necrosis but not other major diseases.

Assuntos

COVID-19; Glucocorticoides; Seguimentos; Glucocorticoides/efeitos adversos; Humanos; SARS-CoV-2; Sobreviventes

Palavras-chave

SARS; avascular necrosis; clinical outcomes; follow-up; glucocorticoids

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: COVID-19 / Glucocorticoides Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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