Metabolism of bifenthrin, ß-cyfluthrin, &#955;-cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes.

Hedges, Laura; Brown, Susan; MacLeod, A Kenneth; Moreau, Marjory; Yoon, Miyoung; Creek, Moire R; Osimitz, Thomas G; Lake, Brian G

Metabolism of bifenthrin, ß-cyfluthrin, λ-cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes.

Hedges, Laura; Brown, Susan; MacLeod, A Kenneth; Moreau, Marjory; Yoon, Miyoung; Creek, Moire R; Osimitz, Thomas G; Lake, Brian G.

Afiliação

Hedges L; Concept Life Sciences (formerly CXR Biosciences Ltd.), Dundee, UK.
Brown S; Concept Life Sciences (formerly CXR Biosciences Ltd.), Dundee, UK.
MacLeod AK; Concept Life Sciences (formerly CXR Biosciences Ltd.), Dundee, UK.
Moreau M; ScitoVation, LLC, Research Triangle Park, NC, USA.
Yoon M; ScitoVation, LLC, Research Triangle Park, NC, USA.
Creek MR; Moire Creek Toxicology Consulting Services, Lincoln, CA, USA.
Osimitz TG; Science Strategies, LLC, Charlottesville, VA, USA.
Lake BG; Faculty of Health and Medical Sciences, University of Surrey, Surrey, UK.

Xenobiotica ; 50(12): 1434-1442, 2020 Dec.

Article em En | MEDLINE | ID: mdl-32672501

Assuntos

Carboxilesterase/metabolismo; Sistema Enzimático do Citocromo P-450/metabolismo; Piretrinas/metabolismo; Animais; Humanos; Masculino; Microssomos Hepáticos/metabolismo; Nitrilas/metabolismo; Ratos

Palavras-chave

Bifenthrin; carboxylesterase; cyphenothrin; cytochrome P450; esfenvalerate; human; pyrethroids; rat; ß-cyfluthrin; λ-cyhalothrin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piretrinas / Sistema Enzimático do Citocromo P-450 / Carboxilesterase Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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