Neonatal Dengue With HLH: Perks of Early Diagnosis and Management.
J Pediatr Hematol Oncol
; 43(6): e770-e773, 2021 08 01.
Article
em En
| MEDLINE
| ID: mdl-32675555
ABSTRACT
BACKGROUND:
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, aggressive syndrome. It can be primary, which involves genetic mutation with an early presentation, or secondary to infections, malignancies, etc., due to absence of immune downregulation. It is a very rare condition in newborns. Dengue is a potential virus causing HLH, but, in newborns, there are only few case reports and limited clinical literature. OBSERVATION Herein, in this report, we highlight a case of neonatal HLH, triggered by perinatal dengue. The neonate manifested clinically within the first week of life, the earliest reported timeline so far in the literature.CONCLUSION:
HLH should be excluded in neonates especially when multisystem involvement cannot be explained by sepsis alone.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dengue
/
Linfo-Histiocitose Hemofagocítica
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Humans
/
Male
/
Newborn
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article