Paeonol inhibits proliferation and induces cell apoptosis of human T24 and 5637 bladder cancer cells in vitro and in vivo.

Zhang, J J; Cai, L J; Pang, K; Dong, Y; Zhang, Z G; Li, B B; Li, R; Han, C H

Zhang, J J; Cai, L J; Pang, K; Dong, Y; Zhang, Z G; Li, B B; Li, R; Han, C H.

Afiliação

Zhang JJ; Department of Urology, The Third Affiliated Hospital of Soochow University, No. 185 Juqian Street, TianNing District, Changzhou City, Jiangsu Province, China.
Cai LJ; Department of Urology, The Affiliated Suqian Hospital of Xuzhou Medical University, Suqian People's Hospital of Nanjing Drum-Tower Hospital Group, No. 138, Huanghe South Road, Sucheng District, Suqian City, Jiangsu Province, China.
Pang K; Jiangsu Normal University Kewen College, No. 101 Shanghai Road, Tongshan New District, Xuzhou City, Jiangsu Province, China.
Dong Y; Department of Urology, The Affiliated Suqian Hospital of Xuzhou Medical University, Suqian People's Hospital of Nanjing Drum-Tower Hospital Group, No. 138, Huanghe South Road, Sucheng District, Suqian City, Jiangsu Province, China.
Zhang ZG; Jiangsu Normal University Kewen College, No. 101 Shanghai Road, Tongshan New District, Xuzhou City, Jiangsu Province, China.
Li BB; Department of Urology, Xuzhou Central Hospital, No. 199, Jiefang South Road, Quanshan District, Xuzhou City, Jiangsu Province, China.
Li R; Department of Urology, Xuzhou Central Hospital, No. 199, Jiefang South Road, Quanshan District, Xuzhou City, Jiangsu Province, China.
Han CH; Department of Urology, Xuzhou Central Hospital, No. 199, Jiefang South Road, Quanshan District, Xuzhou City, Jiangsu Province, China.

Clin Transl Oncol ; 23(3): 601-611, 2021 Mar.

Article em En | MEDLINE | ID: mdl-32691366

Assuntos

Acetofenonas/farmacologia; Antineoplásicos Fitogênicos/farmacologia; Apoptose/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Neoplasias da Bexiga Urinária/patologia; Animais; Caspase 3/análise; Linhagem Celular Tumoral; Citometria de Fluxo; Humanos; Marcação In Situ das Extremidades Cortadas; Técnicas In Vitro; Antígeno Ki-67/análise; Camundongos; Camundongos Nus; Transplante de Neoplasias; Fosfatidilinositol 3-Quinases/metabolismo; Fosforilação/efeitos dos fármacos; Proteínas Proto-Oncogênicas c-akt/metabolismo; Proteínas Proto-Oncogênicas c-bcl-2/análise; Neoplasias da Bexiga Urinária/química; Neoplasias da Bexiga Urinária/tratamento farmacológico; Ensaios Antitumorais Modelo de Xenoenxerto; Proteína X Associada a bcl-2/análise

Palavras-chave

Bladder cancer; Cell apoptosis; Cell proliferation; Paeonol

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetofenonas / Neoplasias da Bexiga Urinária / Apoptose / Proliferação de Células / Antineoplásicos Fitogênicos Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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