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Selective Delivery of Dicarboxylates to Mitochondria by Conjugation to a Lipophilic Cation via a Cleavable Linker.
Prag, Hiran A; Kula-Alwar, Duvaraka; Pala, Laura; Caldwell, Stuart T; Beach, Timothy E; James, Andrew M; Saeb-Parsy, Kourosh; Krieg, Thomas; Hartley, Richard C; Murphy, Michael P.
Afiliação
  • Prag HA; Molecular Research Center, Mitochondrial Biology Unit, Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Kula-Alwar D; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, United Kingdom.
  • Pala L; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
  • Caldwell ST; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
  • Beach TE; Department of Surgery, Cambridge National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge CB2 0QQ, United Kingdom.
  • James AM; Molecular Research Center, Mitochondrial Biology Unit, Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
  • Saeb-Parsy K; Department of Surgery, Cambridge National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge CB2 0QQ, United Kingdom.
  • Krieg T; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, United Kingdom.
  • Hartley RC; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, United Kingdom.
  • Murphy MP; Molecular Research Center, Mitochondrial Biology Unit, Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
Mol Pharm ; 17(9): 3526-3540, 2020 09 08.
Article em En | MEDLINE | ID: mdl-32692564
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Carboxílicos / Cátions / Mitocôndrias Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Carboxílicos / Cátions / Mitocôndrias Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article